Results 91 to 100 of about 6,042,646 (342)

A Novel Method for Indomethacin Determination Based on Graphene Loaded Nickel Oxides Nanoparticles Film

open access: yesInternational Journal of Electrochemical Science, 2018
A novel method was described for sensitive voltammetric determination of indomethacin based on a graphene loaded nickel oxides nanoparticles (Gr-NiO) film by one-step electrodeposition.
Yuxia Liu   +5 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Self-determination and transition to retirement

open access: yes, 2013
Retirement is a major life transition that offers many opportunities for self-determination. In Australia, there is no compulsory retirement age, so workers need to make an active decision to retire.
Gambin, Nicolette   +5 more
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

A "New" Strategy for Afghanistan and Its Region

open access: yes, 2009
The report assesses the strategy of the Obama Administration as stated in early 2009 toward Afghanistan and provides recommendations for Afghanistan and its region. This strategy resembles a strategic framework more than a specific strategy.
Liechtenstein Institute on Self-Determination
core  

A global governance approach to post-colonial self-determination

open access: yes, 2015
Major changes to the interpretation and application of the law of self-determination have taken place since the era of decolonisation. Notably, because most non-selfgoverning territories have attained independence, analyses have shifted by looking at the
Stuart Christopher Wright (7656218)
core   +5 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A New Vision for Afghanistan

open access: yes, 2008
The report assesses progress made and addresses critical issues facing Afghanistan in the areas of security, regional relations, elections, governance and rule of law, the economy and human development, and policy in the region and macro region.
Liechtenstein Institute on Self-Determination
core  

The Importance of Social Media and Religious Perceptions in the Service of Politicians' Communication and Images

open access: yesMedya ve Din Araştırmaları Dergisi
Technological determinism, a theory examining the role of technology in societal development, is a subject of extensive discourse in the internet era. This theory perceives technology as a pivotal force shaping societal progress.
Shener Bilalli
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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