Results 91 to 100 of about 6,042,646 (342)
A novel method was described for sensitive voltammetric determination of indomethacin based on a graphene loaded nickel oxides nanoparticles (Gr-NiO) film by one-step electrodeposition.
Yuxia Liu +5 more
doaj +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Self-determination and transition to retirement
Retirement is a major life transition that offers many opportunities for self-determination. In Australia, there is no compulsory retirement age, so workers need to make an active decision to retire.
Gambin, Nicolette +5 more
core
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
A "New" Strategy for Afghanistan and Its Region
The report assesses the strategy of the Obama Administration as stated in early 2009 toward Afghanistan and provides recommendations for Afghanistan and its region. This strategy resembles a strategic framework more than a specific strategy.
Liechtenstein Institute on Self-Determination
core
A global governance approach to post-colonial self-determination
Major changes to the interpretation and application of the law of self-determination have taken place since the era of decolonisation. Notably, because most non-selfgoverning territories have attained independence, analyses have shifted by looking at the
Stuart Christopher Wright (7656218)
core +5 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The report assesses progress made and addresses critical issues facing Afghanistan in the areas of security, regional relations, elections, governance and rule of law, the economy and human development, and policy in the region and macro region.
Liechtenstein Institute on Self-Determination
core
Technological determinism, a theory examining the role of technology in societal development, is a subject of extensive discourse in the internet era. This theory perceives technology as a pivotal force shaping societal progress.
Shener Bilalli
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source

