Results 101 to 110 of about 2,996,487 (312)
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Toward a Sovereign Afghanistan
Focusing on four key issue areas relevant to the immediate and near future of Afghanistan including governance and economy, identity, reconciliation and reintegration, and the region and macro region, the Liechtenstein Institute on Self-Determination ...
Liechtenstein Institute on Self-Determination
core
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Grand Strategy and Self-Determination
This report is the chair's summary from the colloquium, "Grand Strategy and Self-Determination," sponsored by the Liechtenstein Institute on Self-Determination at Princeton University, November 19-20, 2014.The notions of “grand strategy” and “self ...
Liechtenstein Institute on Self-Determination
core
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Clinical presentation and laboratory determination of Phenobarbital overdose
Objective: Barbiturates as hypnotic drugs are widely used in medicine. They act as sedative or analgesic and are used to control seizure disorders. References show that the number cases of poisoning by this drug is very high.
M Abdollahi +4 more
doaj
Sex determination in mythology and history
The history of ideas on how the sexes became divided spans at least three thousand years. The biblical account of the origin of Eve, and the opinions of the philosophers of classical Greece, have unexpected bearings on present-day ideas.
Mittwoch,Ursula, Mittwoch, U
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source

