Results 111 to 120 of about 2,996,487 (312)

Male-specific phophorylated SR splicing proteins in adult flies of the mediterannean fruitfly Ceratitis capitata.

open access: yes, 2013
Sex determination study on male-specific phophorylated SR splicing proteins in adult flies of the mediterannean fruitfly Ceratitis ...
SALVEMINI, MARCO   +7 more
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Iran's Role and Power in the Region and the International System

open access: yes, 2009
The report contains a series of recommendations related to Iran, specifically in the areas of Iran's relations in its region, Iran's nuclear program and multilateral nuclear diplomacy, and Iran's relations with the EU and the US.
Liechtenstein Institute on Self-Determination
core  

Democracy, Self-Determination and Political Membership [PDF]

open access: yes, 2010
My key question is whether the collective right to self-determination justifies a right on the part of liberal democracies to exclude outsiders from entering and settling within their territorial jurisdiction, from accessing citizenship or from ...
Laws, Edward
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Methods for phase diagram determination.

open access: yes, 2007
Phase diagrams are "maps" materials scientists often use to design new materials. They define what compounds and solutions are formed and their respective compositions and amounts when several elements are mixed together under a certain temperature and ...

core  

EDUCATORS’ PERSPECTIVES AND INSTRUCTION: FACTORS THAT INFLUENCE STUDENTS’ SELF-DETERMINATION SKILLS

open access: yes, 2020
This study was designed to understand the factors that influence educators’ perspectives and amount of instruction of student self-determination skills. A mixed methods correlational survey design was utilized to study these factors. The primary research
Wozniak, Stephanie
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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