Results 141 to 150 of about 1,265,630 (267)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Research on Pork Cut and Freshness Determination Method Based on Computer Vision. [PDF]

Foods
Song S, Guo Q, Duan X, Shi X, Liu Z.
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A minimally invasive marine mammal sex determination method using epidermal tissue recovered from suction-cup tags. [PDF]

PLoS One
Novak SX, Linsky JMJ, Knapp KJ, Parks SE, Wiley D, Cusano DA.   +5 more
europepmc   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Pilot study of a novel resection extent determination method using bone single-photon emission CT-standardized uptake value in medication-related osteonecrosis of the jaw. [PDF]

Dentomaxillofac Radiol
Hayashi N, Matsutomo N, Tokorodani R, Fukami M, Nishimori M, Nakatani K, Yoshioka Y, Hayashi Y, Murakami I, Yamagami T, Yamamoto T, Yamamoto T.   +11 more
europepmc   +1 more source

Development and Validation of 2-Azaspiro [4,5] Decan-3-One (Impurity A) in Gabapentin Determination Method Using qNMR Spectroscopy. [PDF]

Molecules, 2021
Kuz'mina NE, Moiseev SV, Khorolskiy MD, Lutceva AI.   +3 more
europepmc   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Determination method of rational position for working face entries in coordinated mining of section coal pillars and lower sub-layer. [PDF]

Sci Rep
Li X, Huan H, Lin H, Li Z, Du F, Cao Z, Fan X, Ren H.   +7 more
europepmc   +1 more source

Development and Validation of four Nitrosamine Impurities Determination Method in Medicines of Valsartan, Losartan, and Irbesartan with HPLC-MS/MS (APCI). [PDF]

Iran J Pharm Res, 2021
Khorolskiy M, Ramenskaya G, Vlasov A, Perederyaev O, Maslennikova N.   +4 more
europepmc   +1 more source