Results 121 to 130 of about 13,501,965 (257)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Liquid chromatography tandem mass spectrometry for determination of catecholamines using alumina-based extraction method

open access: yes, 2007
Catecholamines including epinephrine, norepinephrine and dopamine are important neurotransmitters in human species. The levels of catecholamines in biologic sample are utilized to diagnose hypertension, pheochromocytoma and neuroblastoma.
石先哲, 许国旺, 顾群, 路鑫
core  

Спосіб визначення міцності загального імунітету (інформаційний лист)

open access: yesAnnals of Mechnikov's Institute
Пропонується для використання у практичній роботі лікарів-імунологів, алергологів, інфекціоністів, ЛОР-фахівців, дерматологів, фахівців з внутрішньої медицини, в освітніх програмах вищих медичних навчальних закладах, в науково-дослідній роботі профільних
Mycola Popov   +6 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

A rapid and cost effective ultrasonic solvent extraction method for determination of λ-cyhalothrin and cypermethrin residues in soil

open access: yes, 2015
An effective, simple, and cost effective ultrasonic solvent extraction procedure was developed for the determination of λ-cyhalothrin and cypermethrin residues in soil by gas chromatography with electron capture detector (GC-ECD).
Zulhilmi, Z.A.M.   +3 more
core  

New spectrophotometric method with KMnO4 for determination of hypochlorite in commercial bleaches

open access: yesBulletin of the Chemical Society of Ethiopia, 2005
Hypochlorite with a strong germicidal and bleaching action forms the active component in most commercial bleaches. The new method, an instrument-based and simple experimental procedure involves the reaction of the hypochlorite with arsenious oxide (As2O3)
P. Gengan, S.B. Jonnalagadda
doaj  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Summary Report: Afghanistan Implementation Colloquium

open access: yes, 2010
The report suggests that perceptions and lack of trust are key issues complicating governance reform in Afghanistan and the transfer of responsibilities for security and development from the international community to the Afghan government.
Liechtenstein Institute on Self-Determination
core   +1 more source

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