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Critical particle size for fractionation by deterministic lateral displacement
Lab on a Chip, 2006The fractionation of small particles in a liquid based on their size in a micropost array by deterministic lateral displacement was recently demonstrated with unprecedented resolution (L. R. Huang, E. C. Cox, R. H. Austin and J. C. Sturm, Science, 2004, 304, 987-990, ).
David W, Inglis +3 more
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Microvesicle fractionation using deterministic lateral displacement effect
The 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS), 2014We demonstrate a novel integrated microfluidic device to separate circulating extracellular vesicles from blood stream using the deterministic lateral displacement principle. The device continuously fractionates extracellular vesicles and cells according to size and membrane flexibility by displacing them perpendicularly to the fluid flow direction in ...
András József Laki +6 more
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Continuous Particle Separation Through Deterministic Lateral Displacement
Science, 2004We report on a microfluidic particle-separation device that makes use of the asymmetric bifurcation of laminar flow around obstacles. A particle chooses its path deterministically on the basis of its size. All particles of a given size follow equivalent migration paths, leading to high resolution.
Lotien Richard, Huang +3 more
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Force driven separation of drops by deterministic lateral displacement
Lab on a Chip, 2012We investigate the separation of drops in force-driven deterministic lateral displacement (f-DLD), a promising high-throughput continuous separation method in microfluidics. We perform scaled-up macroscopic experiments in which drops settle through a square array of cylindrical obstacles.
Timothy, Bowman +2 more
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Separation of deformable particles in deterministic lateral displacement devices
Physical Review E, 2011Using numerical simulations, we study the separation of deformable bodies, such as capsules, vesicles, and cells, in deterministic lateral displacement devices, also known as bump arrays. These arrays comprise regular rows of obstacles such as micropillars whose arrangements are shifted between adjacent rows by a fixed amount. We show that, in addition
Raymond, Quek, Duc Vinh, Le, K-H, Chiam
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Breakdown of deterministic lateral displacement efficiency for non-dilute suspensions: A numerical study [PDF]
Medical Engineering and Physics, 2015 We investigate the effect of particle volume fraction on the efficiency of deterministic lateral displacement (DLD) devices. DLD is a popular passive sorting technique for microfluidic applications.
Rohan Vernekar, Timm Kruger
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Particle separation using virtual deterministic lateral displacement (vDLD)
Lab Chip, 2014Sorting of particles measuring 6.6 μm and 7.0 μm has been achieved in a scheme in which lateral displacement is deterministic.
David J, Collins +2 more
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Tipping the balance of deterministic lateral displacement devices using dielectrophoresis
Lab on a Chip, 2009We report the use of dielectrophoresis (DEP) to achieve tunability, improve dynamic range and open up for the separation of particles with regard to parameters other than hydrodynamic size in deterministic lateral displacement (DLD) devices. DLD devices have been shown capable of rapidly and continuously separating micrometer sized plastic spheres by ...
Jason P, Beech +2 more
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A universal framework for design and manufacture of deterministic lateral displacement chips
Lab on a ChipThis work aims to alleviate the difficulties associated with the design and manufacture of deterministic lateral displacement (DLD) chips.
Aryan Mehboudi +2 more
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High-throughput microalgae sorting based on the deterministic lateral displacement technique
Journal of Chromatography AMicroalgae are a group of photosynthetic organisms that can grow autotrophically, performing photosynthesis to synthesize abundant organic compounds and release oxygen. They are rich in nutritional components and chemical precursors, presenting wide-ranging application prospects.
Liuyong Shi, Hong Yan, Teng Zhou
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