Deterministic Lateral Displacement (DLD) Analysis Tool Utilizing Machine Learning towards High-Throughput Separation [PDF]
Micromachines, 2022 Deterministic lateral displacement (DLD) is a microfluidic method for the continuous separation of particles based on their size. There is growing interest in using DLD for harvesting circulating tumor cells from blood for further assays due to its low ...
Eric Gioe +3 more
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A Novel Microfluidic Strategy for Efficient Exosome Separation via Thermally Oxidized Non-Uniform Deterministic Lateral Displacement (DLD) Arrays and Dielectrophoresis (DEP) Synergy [PDF]
BiosensorsExosomes, with diameters ranging from 30 to 150 nm, are saucer-shaped extracellular vesicles (EVs) secreted by various type of human cells. They are present in virtually all bodily fluids.
Dayin Wang +6 more
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A High-Aspect-Ratio Deterministic Lateral Displacement Array for High-Throughput Fractionation [PDF]
MicromachinesFuture industrial applications of microparticle fractionation with deterministic lateral displacement (DLD) devices are hindered by exceedingly low throughput rates.
Jonathan Kottmeier +4 more
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Two-Dimensional Simulation on the Critical Diameter of Particles in Asymmetric I-Shaped DLD Arrays [PDF]
MicromachinesDeterministic lateral displacement (DLD) is a passive particle separation method based on microfluidic technology, with its separation mechanism primarily relying on particle size differences.
Jiangbo Wu +4 more
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Continuous Size-Based Particle Separation Using Inertial Force and Deterministic Lateral Displacement [PDF]
MicromachinesContinuous, label-free particle separation is essential for a broad range of biochemical and biomedical applications. Here, we present a microfluidic device that integrates inertial focusing and deterministic lateral displacement (DLD) within a compact ...
Yile Xie +6 more
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Using Bayes’ Rule for Analysis of Microfluidic Particle and Cluster Sorting [PDF]
MicromachinesDeterministic lateral displacement (DLD) and related microfluidic sorting devices are typically evaluated based on the size distributions of particles collected at each outlet, even though the more relevant measure of performance is the probability that ...
Elham Akbari +4 more
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A 3D modeling framework for accurate trajectory-based prediction of critical diameter in deterministic lateral displacement microfluidics [PDF]
Microsystems & NanoengineeringDeterministic Lateral Displacement (DLD) is a high-precision microfluidic technique for particle separation based on size differences. However, the lack of an accurate predictive model for the critical diameter (Dc) limits both the design flexibility and
Jin Chen +3 more
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Separation of large droplets from an oil-in-water emulsion using a deterministic lateral displacement (DLD) microfluidic chip [PDF]
Scientific ReportsLong-term stability of oil-in-water (O/W) emulsions is often compromised by the presence of larger droplets, which act as seeds for coalescence and phase separation.
Hyeonji Hong +3 more
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Particle and Cell Separation in Deterministic Lateral Displacement Arrays with Inverse L-Shaped Pillars [PDF]
MicromachinesDeterministic lateral displacement (DLD) has emerged as a powerful microfluidic technique for label-free particle separation with high resolution. Although recent innovations in pillar geometry have broadened its biomedical applications, the fundamental ...
Hao Jiang +4 more
doaj +2 more sources
The Latest Advances in Microfluidic DLD Cell Sorting Technology: The Optimization of Channel Design [PDF]
BiosensorsCell sorting plays a crucial role in both medical and biological research. As a key passive sorting technique in the field of microfluidics, deterministic lateral displacement (DLD) has been widely applied to cell separation and sorting. This review aims
Dan Fan, Yi Liu, Yaling Liu
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