Results 41 to 50 of about 1,426,804 (142)

Combining Electrostatic, Hindrance and Diffusive Effects for Predicting Particle Transport and Separation Efficiency in Deterministic Lateral Displacement Microfluidic Devices

Biosensors, 2020
Microfluidic separators based on Deterministic Lateral Displacement (DLD) constitute a promising technique for the label-free detection and separation of mesoscopic objects of biological interest, ranging from cells to exosomes. Owing to the simultaneous
Valentina Biagioni, Giulia Balestrieri, Alessandra Adrover, Stefano Cerbelli   +3 more
doaj   +1 more source

Microfluidic Coupling of Step Emulsification and Deterministic Lateral Displacement for Producing Satellite-Free Droplets and Particles

Micromachines, 2023
Step emulsification, which uses a geometry-dependent mechanism for generating uniformly sized droplets, has recently gained considerable attention because of its robustness against flow fluctuations.
Guangchong Ji, Yusuke Kanno, Takasi Nisisako   +2 more
doaj   +1 more source

A Two-Stage Separation of Circulating Tumor Cells Based on Deterministic Lateral Displacement and Dielectrophoresis Techniques

IEEE Access, 2021
Circulating tumor cells (CTCs) are cancer cells that fall off from cancer lesions and enter the blood of human extracorporeal circulation. They are the early basis of judging cancer metastasis. However, CTCs are extremely rare, there is a great challenge
Yanjuan Wang, Chengxiao Wang, Yunfei Zhang, Meiqi Han, Yangjinyu Li, Shanyu Jin, Haiqi He   +6 more
doaj   +1 more source

Multidirectional sorting modes in deterministic lateral displacement devices [PDF]

, 2008
Deterministic lateral displacement (DLD) devices separate micrometer-scale particles in solution based on their size using a laminar microfluidic flow in an array of obstacles.
Heller, Martin, Henrik Bruus, Bruus, Henrik, Heiner Linke, Long, B.R., Brian R. Long, Linke, H., Jonas O. Tegenfeldt, Jason P. Beech, Long, Brian R, Beech, J.P., Linke, Heiner, Tegenfeldt, Jonas, Tegenfeldt, J.O., Beech, Jason, Martin Heller   +15 more
core   +1 more source

Deterministic Lateral Displacement Microfluidic Chip for Minicell Purification

Micromachines, 2022
Deterministic lateral displacement (DLD) is a well-known microfluidic technique for particle separation with high potential for integration into bioreactors for therapeutic applications.
Ahmad Sherbaz, Büşra M. K. Konak, Pegah Pezeshkpour, Barbara Di Ventura, Bastian E. Rapp   +4 more
doaj   +1 more source

Geometric structure design of passive label-free microfluidic systems for biological micro-object separation

Microsystems & Nanoengineering, 2022
Passive and label-free microfluidic devices have no complex external accessories or detection-interfering label particles. These devices are now widely used in medical and bioresearch applications, including cell focusing and cell separation.
Hao Tang, Jiaqi Niu, Han Jin, Shujing Lin, Daxiang Cui   +4 more
doaj   +1 more source

Label-free enrichment of functional cardiomyocytes using microfluidic deterministic lateral flow displacement. [PDF]

PLoS ONE, 2012
Progress in cardiac cell replacement therapies and tissue engineering critically depends on our ability to isolate functional cardiomyocytes (CMs) from heterogeneous cell mixtures.
Boyang Zhang, James V Green, Shashi K Murthy, Milica Radisic   +3 more
doaj   +1 more source

Understanding extracellular vesicle biology, isolation, and characterization: The theory of EV‐erything

Periodontology 2000, EarlyView.
Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad, Nima Farshidfar, Nathan E. Estrin, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +6 more
wiley   +1 more source

Charge-Based Separation of Micro- and Nanoparticles

Micromachines, 2020
Deterministic Lateral Displacement (DLD) is a label-free particle sorting method that separates by size continuously and with high resolution. By combining DLD with electric fields (eDLD), we show separation of a variety of nano and micro-sized particles
Bao D. Ho, Jason P. Beech, Jonas O. Tegenfeldt   +2 more
doaj   +1 more source

How is Nanoarchitectonics Shaping Extracellular Vesicle Research?

Advanced Healthcare Materials, Volume 15, Issue 36, 25 September 2026.
The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake, Md Shahriar A. Hossain, Chia‐Hung Liu, Carlos Salomon, Yusuke Yamauchi, Mostafa Kamal Masud   +5 more
wiley   +1 more source