Results 21 to 30 of about 152,176 (234)

Design and Implementation of a New Type of Gastrointestinal Robot Wireless Power Transmission System

Shanghai Jiaotong Daxue xuebao, 2022
In order to ensure the stable operation of the miniature gastrointestinal robot inside the human body, a new type of wireless power transmission (WPT) system is presented.
FU Wenhao, JIANG Pingping, YAN Guozheng, PENG Yuqi, FEI Qian, ZHUANG haoyu
doaj   +1 more source

Detoxification

, 2014
Citation: 'detoxification' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.D01644 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
Wilma Silvia CR, Ravish H
  +4 more sources

Development of a growth-coupled selection platform for directed evolution of heme biosynthetic enzymes in Corynebacterium glutamicum

Frontiers in Bioengineering and Biotechnology, 2023
Heme is an important tetrapyrrole compound, and has been widely applied in food and medicine industries. Although microbial production of heme has been developed with metabolic engineering strategies during the past 20 years, the production levels are ...
Yingyu Zhou, Yingyu Zhou, Jiuzhou Chen, Jiuzhou Chen, Wei Pu, Wei Pu, Ningyun Cai, Ningyun Cai, Bin Che, Bin Che, Jinxing Yang, Jinxing Yang, Mengmeng Wang, Mengmeng Wang, Shasha Zhong, Shasha Zhong, Xingtao Zuo, Xingtao Zuo, Depei Wang, Yu Wang, Yu Wang, Ping Zheng, Ping Zheng, Jibin Sun, Jibin Sun   +24 more
doaj   +1 more source

Disarming the Host: Detoxification of Plant Defense Compounds During Fungal Necrotrophy

Frontiers in Plant Science, 2021
While fungal biotrophs are dependent on successfully suppressing/subverting host defenses during their interaction with live cells, necrotrophs, due to their lifestyle are often confronted with a suite of toxic metabolites. These include an assortment of
Nathaniel M. Westrick, Damon L. Smith, Mehdi Kabbage   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Relationship between different levels of internet use and depressive tendencies in Chinese college students: the chain mediating effect based on physical activity and social adaptability

BMC Psychology
Objective To investigate the relationship between internet use, physical activity, social adaptability, and depressive tendencies of college students, and to reveal the “advantages” and “disadvantages” of internet use around the “dose-effect”. Method The
Kun Wang, Yan Li, Hengxu Liu, Tingran Zhang, Jiong Luo   +4 more
doaj   +1 more source

Human colonocyte detoxification [PDF]

Gut, 1997
Detoxification or biotransformation of drugs and xenobiotics are usually linked with liver metabolism, yet colonocytes of the gastrointestinal tract have an equal capacity to mediate these processes.1 2 This brief overview specifically discusses the ability of human colonocytes, but not other tissues, to detoxify chemical agents and relates pertinent ...
Roediger, W., Babidge, W.
openaire   +3 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Influence of Sports Intervention on the Mental Health of College Students in the Background of COVID-19 :A Systematic Review

Quality in Sport
Objective: This review aims to understand the mental health status of college students during the popularity of covid-19, and explore the impact of sports intervention on College Students' mental health and its path mechanism through a literature review.
Yi Yang, Changhong Wu, Liang Sun, Chuanqiushui Wang, Jiong Luo   +4 more
doaj   +1 more source