Results 131 to 140 of about 17,466 (191)

OTUD5 maintains STAT1/2 stability and promotes IFNγ-driven intestinal inflammation. [PDF]

J Biol Chem
Guan H, Cai C, Wang J, Liu Z, Peng J, Bai X, Wu L, Jiang K, Zhen X, Yu C, Zhang P, Shen Z.   +11 more
europepmc   +1 more source

DUB3 is a MAGEA3 deubiquitinase and a potential therapeutic target in hepatocellular carcinoma

Summary: Although melanoma-associated antigen A3 and A6 (MAGEA3/6)-specific tumor vaccines have shown antitumor effects in melanoma and non-small cell lung cancer (NSCLC), many cancers do not respond because MAGEA3 can promote cancer without triggering ...
Meijun Liu, Yuanhong Chen, Yuan Quan, Feng Gao, Peijing Zhang, Yan He   +5 more
core   +1 more source

The role of USP19 in human diseases: from molecular function to clinical relevance. [PDF]

Front Immunol
Wang Q, Cao H, Wei H, Wang X, Luo T, Yin J.   +5 more
europepmc   +1 more source

SFRP2 Potentiates Metastasis of Colon Cancer by Enhancing Snai1 Protein Stability via USP11. [PDF]

J Cell Mol Med
Kuang Y, Liu X, Ke M, Chang Z, Jia B, Li B, Qian H.   +6 more
europepmc   +1 more source

Oncogenic USP3 promotes hepatocellular carcinoma progression via K11/K48-specific deubiquitination and stabilization of YAP. [PDF]

iScience
Peng Y, Nie H, Li X, Tao Y, Zhou Y.
europepmc   +1 more source

MAGEC2 promotes tumorigenesis in multiple myeloma through USP16-mediated deubiquitination and stabilization of c-Myc. [PDF]

Exp Hematol Oncol
Liu Z, Hu T, Min J, Wang C, Cao Y, Guo M, Qian J, Gu C, Yang Y.   +8 more
europepmc   +1 more source

Host OTUB2 and viral PLpro stabilize NSP8 to promote SARS-CoV-2 replication. [PDF]

Virol Sin
Gao W, Wang H, Xin J, Gu C, Qiu L, Zhang X, Wang C, Zhang Q, Li S, Li G, Zhang W.   +10 more
europepmc   +1 more source

The deubiquitinating enzyme USP42 promotes lung adenocarcinoma progression through PTGS2. [PDF]

J Mol Histol
Ye H, Shen J, Liu D, Mao Q, Wang H, Wang J, Liu X.   +6 more
europepmc   +1 more source

OTULIN: a master regulator of linear ubiquitin homeostasis in immune signaling, inflammation, and disease. [PDF]

Front Immunol
Zhang Z, Lyu J, Bai Y, Guo Z, Bo Q, Liu K, Dai X.   +6 more
europepmc   +1 more source

Structure-Guided Discovery and Biochemical Validation of Novel Small-Molecule Inhibitors Predicted to Target the CCHFV OTU Protease Y89-W99 Pocket. [PDF]

Int J Mol Sci
Akgöl S, Kocabaş F.
europepmc   +1 more source