Results 131 to 140 of about 878,178 (411)
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Hartz IV – Welfare to Work in Germany [PDF]
Workfare, Wohlfahrtstheorie, Arbeitslosigkeit, Arbeitslosenversicherung, Deutschland, Welfare economics, Unemployment, Unemployment insurance ...
Wolfgang Ochel
core
Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
Regional Infrastructure Policy and its Impact on Productivity: A Comparison of Germany and France [PDF]
This paper describes the different institutional frameworks for infrastructure policy in Germany and France. The economic effects of infrastructure are estimated econometrically for German and French regions.
Andreas Stephan
core
Molecular Oncology, EarlyView.Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho +11 more
wiley +1 more source
Marie-Theres Federhofer, Sabine Meyer (Hgg.): Mit dem Buch in der Hand. Beiträge zur deutsch-skandinavischen Buch- und Bibliotheksgeschichte. / A Book in Hand. German- Scandinavian Book and Library History. Berliner Beiträge zur Skandinavistik, Band 31. Berlin: Nordeuropa-Institut 2021, 327 S. [PDF]
NORDEUROPAforum - Zeitschrift für Kulturstudien, 2023 Sarah Timme
doaj +1 more source
Globalization of the automobile industry : traditional locations under pressure?. [PDF]
n.a.Kraftfahrzeugindustrie; Globalisierung; Internationaler Wettbewerb; Standortwettbewerb; Beschäftigungseffekt; Deutschland; USA; Japan;
Nunnenkamp, Peter, Spatz, Julius
core
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source