Results 81 to 90 of about 953,705 (390)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

El binomio Enrique Morente - Antonio Robledo: una síntesis musical inédita y precursora.

open access: yesMúsica Oral del Sur, 2021
Los años de colaboración entre Morente y Robledo muestran resultados musicales inéditos. La experimentación que Robledo y Morente acometieron en sus obras colectivas es un resultado del proceso creativo que iniciaron años antes trabajando con Susana ...
Isora Castilla Rocha
doaj  

Trade policy in West Germany. [PDF]

open access: yes
Außenwirtschaftspolitik; Deutschland;
Heitger, Bernhard   +4 more
core  

The Alternative for Germany’s radicalization in historical-comparative perspective [PDF]

open access: yes, 2017
This article chronicles the AfD’s rightward repositioning and compares it with the programmatic development of three postwar German parties on the ideological wings.
Bortfeldt Heinrich   +11 more
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Klimawandel in Deutschland: Entwicklung, Folgen, Risiken und Perspektiven

open access: yes, 2017
Erstmals tragt dieses nationale Assessment den Forschungsstand zum Klimawandel umfassend fur alle Themenbereiche und gesellschaftlichen Sektoren zusammen.
Guy P. Brasseur   +2 more
semanticscholar   +1 more source

National Institutional Systems in Global Competition and the Inertia of German Labour Market Institutions [PDF]

open access: yes
Arbeitsverwaltung, Internationaler Wettbewerb, Deutschland, Welt, Labour administration, Global competition, Germany ...
Wolfgang Ochel
core  

Social Security of Citizens in the Manifesto of the Christian Democratic Union and the Christian Social Union for the 2017 Parliamentary Election in Germany [PDF]

open access: yes, 2018
This article aims to analyze the common manifesto of the Christian Democratic Union of Germany and the Christian-Social Union in Bavaria regarding social security, with regard to the elections to the German parliament in 2017. The basic assumption was to
Plecka, Danuta, Rutkowska, Patrycja
core   +3 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

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