Results 101 to 110 of about 14,908,548 (354)

In Vitro Evolution of Antibodies Inspired by In Vivo Evolution

open access: yesFrontiers in Immunology, 2018
In vitro generation of antibodies often requires variable domain sequence evolution to adapt the protein in terms of affinity, specificity, or developability.
Helena Persson   +8 more
doaj   +1 more source

Smooth quasi-developable surfaces bounded by smooth curves

open access: yes, 2019
Computing a quasi-developable strip surface bounded by design curves finds wide industrial applications. Existing methods compute discrete surfaces composed of developable lines connecting sampling points on input curves which are not adequate for ...
Bo, Pengbo   +2 more
core  

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez   +13 more
wiley   +1 more source

Feeling Safe in Urban Estates: Learning from Riverwood, Sydney [PDF]

open access: yes, 2020
Feeling safe is a necessity for quality of life. Conversely, feeling unsafe has a substantial impact on residents’ quality of life. How does design impact on the perception of safety, and moreover, how can design reduce incidences of ...
Arasteh, Samaneh
core  

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack   +12 more
wiley   +1 more source

Empirical Investigation into the Limitations of the Normative Paired Sales Adjustment Method [PDF]

open access: yes
This study investigates the normative paired sales adjustment method employed by appraisers in the sales comparison approach. It finds that the method fails to account for the diminishing marginal price effects of property attributes.
Marvin L. Wolverton
core  

Improved Outcomes for Older Children, Adolescents, and Young Adults With Neuroblastoma in the Post‐Immunotherapy Era: An Updated Report From the International Neuroblastoma Risk Group

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell   +14 more
wiley   +1 more source

On the developability of subalgebroids

open access: yes, 2004
In this paper, the Almeida-Molino obstruction to developability of transversely complete foliations is extended to Lie ...
Moerdijk, I., Mrcun, J.
core   +2 more sources

On paratopological groups [PDF]

open access: yes, 2013
In this paper, we firstly construct a Hausdorff non-submetrizable paratopological group $G$ in which every point is a $G_{\delta}$-set, which gives a negative answer to Arhangel'ski\v{\i}\ and Tkachenko's question [Topological Groups and Related ...
Lin, Fucai, Liu, Chuan
core  

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