Results 131 to 140 of about 23,042,479 (320)
Flattening developable bi-parametric surfaces
, 1996 This paper describes a computer method for transforming an arbitrary developable surface into a flattened pattern. Developable surfaces are a special class of ruled surfaces. The Gaussian curvature of any point of the developable surfaces is zero.
Tan, ST, Gan, MC, Chan, KW
core +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Generating and flattening developable surfaces
, 1994 In this paper, methods for generating and flattening developable surfaces by means of two given directrix curves have been investigated. By finding the two end points of every generatrix, a developable surface may be formed.
Tan, ST, Gan, MC, Chan, KW
core
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Slant spacelike ruled surfaces and their Bertrand offsets
Frontiers in PhysicsIn this work, we investigate the synthesis problem of slant spacelike ruled surfaces and associated Bertrand offsets (BO) in E13 (Minkowsk 3-space). We provide the parametric equation for a non-developable spacelike ruled surface (SLRS) by using the ...
Areej A. Almoneef, Rashad A. Abdel-Baky
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
, 2005 Recurring to some excellent geometric and algebraic properties of Poisson curves, we present an algorithm that generates a developable Poisson surface through a Poisson curve of arbitrary degree.
Xingwang Zhang, Guojin Wang
core
On the developable ruled surfaces Kinematically generated in Minkowski 3-Space
Kuwait Journal of Science, 2014 In this paper, we present a method to be developable of a ruled surface, generated in Minkowski 3-space R corresponding to the dual Lorentzian curves according to E. Study's transference principle and some theorems and examples.
HACI BAYRAM KARADAg١ +2 more
doaj
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source