Results 61 to 70 of about 23,042,479 (320)

Bridging the gap between rectifying developables and tangent developables: a family of developable surfaces associated with a space curve

open access: yesProceedings of the Royal Society A, 2021
There are two familiar constructions of a developable surface from a space curve. The tangent developable is a ruled surface for which the rulings are tangent to the curve at each point and relative to this surface the absolute value of the geodesic ...
Brian Seguin, Yi-chao Chen, E. Fried
semanticscholar   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

The Ruled Surfaces According to Bishop Frame in Minkowski 3-Space

open access: yesAbstract and Applied Analysis, 2013
We investigate the ruled surfaces generated by a straight line in Bishop frame moving along a spacelike curve in Minkowski 3-space. We obtain the distribution parameters, mean curvatures.
Nural Yüksel
doaj   +1 more source

Timelike-Ruled and Developable Surfaces in Minkowski 3-Space E13

open access: yesFrontiers in Physics, 2022
In this study, the timelike-ruled and developable surfaces are constructed in Minkowski 3-space E13. Using the E. Study map, we demonstrate that dual forms of timelike-ruled and developable surfaces can be obtained from the coordinates and first ...
Fatemah Mofarreh
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Design Support of function of brassiere cup using gaussian process regression

open access: yesNihon Kikai Gakkai ronbunshu, 2021
A method to design the function of the brassiere cup shape as developable surfaces and its developed shape using Gaussian Process Regression is proposed.
Kotaro YOSHIDA   +3 more
doaj   +1 more source

Shape approximation by developable wrapping

open access: yesACM Transactions on Graphics, 2020
We present an automatic tool to approximate curved geometries with piece-wise developable surfaces. At the center of our work is an algorithm that wraps a given 3D input surface with multiple developable patches, each modeled as a discrete orthogonal ...
A. Ion   +3 more
semanticscholar   +1 more source

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