Results 61 to 70 of about 4,484,193 (288)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Spacelike Ruled Surface In Hyperbolic 3-Space
Cumhuriyet Science Journal, 2018 In this paper in Hyperbolic space , we study a spacelike ruled surfaces. A spacelike ruledsurface in is acquired by aspacelike geodesic moving along a spacelike curve.
Tuğba Mert
doaj +1 more source
Additive Manufacturing of Conformal Microstrip Antenna Using Piezoelectric Nozzle Array
Applied Sciences, 2020 Inkjet printing technology is widely used in the manufacture of conformal structures, such as load-bearing antennas or frequency-selective surface radomes.
Zheng Li +6 more
doaj +1 more source
A method of the determination of a developable ruled surface
, 1999 Using dual vector calculus, a method of determination of a developable ruled surface is presented. The dual vectorial expression of a developable ruled surface m(t, u) = p(t) + ux(t), p(t) is called the base curve of m(t, u), obtained from the ...
Kose, O
core +1 more source
Construction of Developable Surfaces with Two Director Curves
Structural Mechanics of Engineering Constructions and BuildingsAn analysis of a number of published materials regarding four types of developable surfaces with two director (supporting) algebraic curves of the second order lying in parallel or in intersecting planes has been conducted.
Sergey N. Krivoshapko
doaj +1 more source
Paper strips driven design: Application on doubly curved surfaces [PDF]
FME Transactions, 2017 In this paper, we address the challenge of overcoming the problem of developing doubly curved surfaces in product design. Product design uses two kinds of surfaces, developable surfaces and non-developable surfaces, which are also called singly and ...
Čučaković Aleksandar A. +2 more
doaj
Smarandache Ruled Surfaces according to Darboux Frame in E3
Journal of Mathematics, 2021 This paper presents a new approach of constructing special ruled surfaces and aims to study their developability and minimalist conditions. Our concept opens opportunities for application in engineering, surface modeling, and architectural design.
Soukaina Ouarab
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source