Results 121 to 130 of about 975,123 (280)
Involute Partner-Ruled Surfaces Formed by Involutes of Spacelike Curves in Minkowski Three-Space
AxiomsWe introduced the concept of involute partner-ruled surfaces, which are formed by the involutes of spacelike curves and additional conditions ensuring the presence of definite surface normals in Minkowski three-space.
Özgür Boyacıoğlu Kalkan +3 more
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Developable Surfaces: Properties, Representations and Methods of Design
, 1992 v, 34 p.General Motors is interested in designing developable surfaces using computers. A developable surface is one that can be formed by bending a sheet of thin planar material.
Mancewicz, Martha J.
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Möbius bands, unstretchable material sheets and developable surfaces. [PDF]
Proc Math Phys Eng Sci, 2016 Chen YC, Fried E.
europepmc +1 more source
Designing Developable Mechanisms on Conical and Cylindrical Developable Surfaces
, 2020 The research results presented in this thesis provide tools and methods to aid in the design of developable mechanisms. This work will help engineers design compact mechanisms onto developable surfaces, making it possible for them to be used in future ...
Hyatt, Lance Parker
core
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Hyperbolic framed surfaces in hyperbolic 3-space
Demonstratio MathematicaWe define a hyperbolic framed surface with a moving frame in hyperbolic 3-space. By the existence and uniqueness theorems for hyperbolic framed surfaces, we know that the hyperbolic framed surface is uniquely determined by basic invariants up to a ...
Zhou Anjie, Pei Donghe
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Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source