Results 41 to 50 of about 1,745,656 (286)

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source

Better statistical reporting does not lead to statistical rigour: lessons from two decades of pseudoreplication in mouse-model studies of neurological disorders

Molecular Autism
Background Accurately determining the sample size (“N”) of a dataset is a key consideration for experimental design. Misidentification of sample size can lead to pseudoreplication, a process of artificially inflating the number of experimental replicates
Constantinos Eleftheriou, Sarah Giachetti, Raven Hickson, Laura Kamnioti-Dumont, Robert Templaar, Alina Aaltonen, Eleni Tsoukala, Nawon Kim, Lysandra Fryer-Petridis, Chloe Henley, Ceren Erdem, Emma Wilson, Beatriz Maio, Jingjing Ye, Jessica C. Pierce, Kath Mazur, Lucia Landa-Navarro, Nina G. Petrović, Sarah Bendova, Hanan Woods, Manuela Rizzi, Vanesa Salazar-Sanchez, Natasha Anstey, Antonios Asiminas, Shinjini Basu, Sam A. Booker, Anjanette Harris, Sam Heyes, Adam Jackson, Alex Crocker-Buque, Aoife C. McMahon, Sally M. Till, Lasani S. Wijetunge, David JA Wyllie, Catherine M. Abbott, Timothy O’Leary, Peter C. Kind   +36 more
doaj   +1 more source

An eye tracking based virtual reality system for use inside magnetic resonance imaging systems

Scientific Reports, 2021
Patients undergoing Magnetic Resonance Imaging (MRI) often experience anxiety and sometimes distress prior to and during scanning. Here a full MRI compatible virtual reality (VR) system is described and tested with the aim of creating a radically ...
Kun Qian, Tomoki Arichi, Anthony Price, Sofia Dall’Orso, Jonathan Eden, Yohan Noh, Kawal Rhode, Etienne Burdet, Mark Neil, A. David Edwards, Joseph V. Hajnal   +10 more
doaj   +1 more source

Proliferation versus Differentiation: Redefining Retinoic Acids Role. [PDF]

, 2018
Retinoic acid is commonly used in culture to differentiate stem cells into neurons and has established neural differentiation functions in vivo in developing and adult organisms. In this issue of Stem Cell Reports, Mishra et al.
Mosher, Kira, SCHAFFER, David
core   +1 more source

Prevalence and Trajectory of Household Material Hardship Among Children With Advanced Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Families of children with advanced cancer living in poverty experience inferior outcomes including poor parent mental health and worse child quality of life. Household material hardship (HMH: food, housing, transportation, and/or utility insecurity) is a modifiable poverty exposure—and potential intervention target—that ...
Sarah Wright, Morgan A. Paul, Selena Murcia Mendez, Emily Jones, Lucille Lokko, Chelsea Heneghan, Nicholas Purol, Morgan Arnold, Rahela Aziz‐Bose, Colleen A. Kelly, Sandi L. Pruitt, Joanne Wolfe, Kira Bona, Puja J. Umaretiya   +13 more
wiley   +1 more source

Exploring the multiple-hit hypothesis of preterm white matter damage using diffusion MRI

NeuroImage: Clinical, 2018
Background: Preterm infants are at high risk of diffuse white matter injury and adverse neurodevelopmental outcome. The multiple hit hypothesis suggests that the risk of white matter injury increases with cumulative exposure to multiple perinatal risk ...
Madeleine L. Barnett, Nora Tusor, Gareth Ball, Andrew Chew, Shona Falconer, Paul Aljabar, Jessica A. Kimpton, Nigel Kennea, Mary Rutherford, A. David Edwards, Serena J. Counsell   +10 more
doaj   +1 more source

Parental age effects on neonatal white matter development

NeuroImage: Clinical, 2020
Objective: Advanced paternal age is associated with poor offspring developmental outcome. Though an increase in paternal age-related germline mutations may affect offspring white matter development, outcome differences could also be due to psychosocial ...
Oliver Gale-Grant, Daan Christiaens, Lucilio Cordero-Grande, Andrew Chew, Shona Falconer, Antonios Makropoulos, Nicholas Harper, Anthony N Price, Jana Hutter, Emer Hughes, Suresh Victor, Serena J Counsell, Daniel Rueckert, Joseph V Hajnal, A David Edwards, Jonathan O'Muircheartaigh, Dafnis Batalle   +16 more
doaj   +1 more source

Imaging brain development: The adolescent brain

NeuroImage, 2012
The past 15 years have seen a rapid expansion in the number of studies using neuroimaging techniques to investigate maturational changes in the human brain. In this paper, I review MRI studies on structural changes in the developing brain, and fMRI studies on functional changes in the social brain during adolescence.
openaire   +2 more sources

On the robustness of brain gain estimates [PDF]

Recent theoretical studies suggest that migration prospects can raise the expected return to human capital and thus foster education investment at home or, in other words, induce a brain gain.
Frederic Docquier, Hillel Rapoport, Michel Beine   +2 more
core   +6 more sources