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Eight Questions about Brain Drain [PDF]
High-skilled emigration is an emotive issue that in popular discourse is often referred to as brain drain, conjuring images of extremely negative impacts on developing countries. Recent discussions of brain gain, diaspora effects, and other advantages of
David McKenzie, John Gibson
core +6 more sources
Baby Open Brains: An open-source dataset of infant brain segmentations
Scientific DataReproducibility of neuroimaging research on infant brain development remains limited due to highly variable processing approaches. Progress towards reproducible pipelines is limited by a lack of benchmarks such as gold-standard brain segmentations. These
Eric Feczko +38 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Molecular signatures of cortical expansion in the human foetal brain
Nature CommunicationsThe third trimester of human gestation is characterised by rapid increases in brain volume and cortical surface area. Recent studies have revealed a remarkable molecular diversity across the prenatal cortex but little is known about how this diversity ...
G. Ball +12 more
doaj +1 more source
On the need for bundle-specific microstructure kernels in diffusion MRI
NeuroImage, 2020 Probing microstructure with diffusion magnetic resonance imaging (dMRI) on a scale orders of magnitude below the imaging resolution relies on biophysical modelling of the signal response in the tissue.
Daan Christiaens +6 more
doaj +1 more source
The labial gene is required to terminate proliferation of identified neuroblasts in postembryonic development of the Drosophila brain [PDF]
, 2012 The developing brain of Drosophila has become a useful model for studying the molecular genetic mechanisms that give rise to the complex neuronal arrays that characterize higher brains in other animals including mammals.
Bello, B. C., Kuert, P. A., Reichert, H.
core +3 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
‘We knew it was a totally at random thing’: parents’ experiences of being part of a neonatal trial
Trials, 2017 Background Studies exploring parents’ trial experiences generally relate to their understanding of the consent process and the development of researcher strategies to facilitate recruitment and retention.
Merryl Harvey +3 more
doaj +1 more source
Brain drain in developing countries [PDF]
Relying on an original data set on international migration by educational attainment for 1990 and 2000, we analyze the determinants of the brain drain from developing countries.
Abdeslam, MARFOUK +2 more
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