Results 41 to 50 of about 2,326,033 (267)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The cascade of global trade to large climate forcing over the Tibetan Plateau glaciers

Nature Communications, 2019
To trace the sources of Black Carbon being transported into the Tibetan Plateau is crucial for guiding an effective mitigation strategy. Here the authors utilized the adjoint of the Goddard Earth Observing System-Chem model and find that international ...
Kan Yi, Jing Meng, Haozhe Yang, Cenlin He, Daven K. Henze, Junfeng Liu, Dabo Guan, Zhu Liu, Lin Zhang, Xi Zhu, Yanli Cheng, Shu Tao   +11 more
doaj   +1 more source

Different Patterns in Daytime and Nighttime Thermal Effects of Urbanization in Beijing-Tianjin-Hebei Urban Agglomeration

Remote Sensing, 2017
Surface urban heat island (SUHI) in the context of urbanization has gained much attention in recent decades; however, the seasonal variations of SUHI and their drivers are still not well documented.
Guosong Zhao, Jinwei Dong, Jiyuan Liu, Jun Zhai, Yaoping Cui, Tian He, Xiangming Xiao   +6 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

A psychophysical measurement on subjective well-being and air pollution

Nature Communications, 2019
Air pollution can affect people’s emotional status and well-being. Here, the authors simulate fixed-scene images to show that under the atmospheric conditions in Beijing, negative emotions occur when air quality index of PM2.5 increases to approximately ...
Yuan Li, Dabo Guan, Yanni Yu, Stephen Westland, Daoping Wang, Jing Meng, Xuejun Wang, Kebin He, Shu Tao   +8 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Biosimilars of anti-VEGF agents in retinal diseases: a narrative review of regulatory, clinical, and pharmacoeconomic aspects

International Journal of Retina and Vitreous
Background Anti-vascular endothelial growth factor (anti-VEGF) agents are the cornerstone therapy for retinal vascular diseases including neovascular age-related macular degeneration, diabetic macular edema, and retinal vein occlusion.
Yuan Zong, Qiwei Fan, Lijun Huang
doaj   +1 more source

Optimization of land use to accommodate nutritional transformation of food systems: a case study from the Beijing–Tianjin–Hebei region

Frontiers in Sustainable Food Systems
The transformation and reconstruction of China’s food system not only faces many risks, such as the unceasing growth of food consumption on the demand side and the structural imbalance of dietary nutrition, but also must address serious challenges, such ...
Wenxuan Wang, Wenxuan Wang, Zhuoyuan Gu, Ze Han, Zhihui Li, Zhihui Li   +5 more
doaj   +1 more source