Results 121 to 130 of about 1,212,018 (258)

Next generation of electronic medical record search engines to support chart reviews: A systematic user study and future research direction

open access: yesJournal of Economy and Technology
Objective: Little research has been done on the user-centered document ranking approach, especially in a crowdsourcing chart review environment. As the starting point of designing and implementing the next generation of Electronic Medical Record (EMR ...
Cheng Ye, Daniel Fabbri
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Ranking of EU countries in terms of the value of environmental governance indicators in 2010 and 2015

open access: yesEconomics and Environment, 2018
The purpose of this study is to analyze the indicators of environmental governance as one of the elements of sustainable development. The results of the study show the ranking of EU countries in terms of the value of selected indicators in the years ...
Anna Iwacewicz-Orłowska   +1 more
doaj  

Optimizing the new formulation of the United Nations' human development index: An empirical view from data envelopment analysis. [PDF]

open access: yes
In this paper, we propose a new way to simulate an optimal Human Development Index [HDI]. Indeed, the formulation of the original HDI established by the United Nations Development Programme [UNDP] relies on a major methodological shortcoming, namely the ...
Jean-François Hoarau   +1 more
core  

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Poverty, Income Distribution and Social Development in Lahore [PDF]

open access: yes
In this paper we present a comparative analysis of poverty and income inequality prevalent in the seven towns of Lahore. Further, an analysis of gender inequality and overall social development is presented by considering education, health, and labor ...
Hyder, Kalim, Sikander, Muhammad Usman
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Uncertainty and Sensitivity Analysis of the Human Development Index [PDF]

open access: yes
This paper discusses the methodological judgments made during the development of the Human Development Index (HDI), and analyzes the quantitative and qualitative impact of different methodological choices on the HDI scores, as well as on the associated ...
Clara García Aguña, Milorad Kovacevic
core  

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

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