α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
RDC review Jan 2004: Bulletin for Research and Development UiTM
, 2004 IRDC Review takes a short walk down memory lane to recap on some of the significant issues and events that impacted the Institute in the past year. Indeed it has been a year of achievements at the Institute of Research, Development and Commercialisation (
UiTM, Institute of Research, Development and Commercialization
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Health research-strengthening and capacity development: Research support system model in an academic healthcare system. [PDF]
Qatar Med J, 2022 Irfan FB +3 more
europepmc +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Governmental aspects of development in the Bicol Region
, 1974 Phase I of a three-part study for the Cooperative Regional Development ProjectThis study is concerned with development in Bicol, focusing on the public sector's approach to development therein. Discusses such components of program formulation as politics,
National Development Research Centre +1 more
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Shifting social norms to prevent age-disparate transactional sex in Tanzania: what we can learn from intervention development research. [PDF]
Front Psychol, 2023 Howard-Merrill L +8 more
europepmc +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Multiple Gas Seepage Mechanisms and Production Development Research for Shale Gas Reservoirs from Experimental Techniques and Theoretical Models. [PDF]
ACS Omega, 2023 Hu Z +8 more
europepmc +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Trends and status in resources security, ecological stability, and sustainable development research: a systematic analysis. [PDF]
Environ Sci Pollut Res Int, 2022 Kang X, Wang M, Lin J, Li X.
europepmc +1 more source