Results 151 to 160 of about 19,882,836 (301)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

COVID-19: the impact of a global crisis on sustainable development research. [PDF]

Sustain Sci, 2021
Leal Filho W, Azul AM, Wall T, Vasconcelos CRP, Salvia AL, do Paço A, Shulla K, Levesque V, Doni F, Alvarez-Castañón L, Mac-Lean C, Avila LV, Damke LI, Castro P, Azeiteiro UM, Fritzen B, Ferreira P, Frankenberger F.   +17 more
europepmc   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Urban and Rural Population and Development Research on Medical Coordination: In View of Dalian 2008-2017 Official Statistics. [PDF]

Int J Environ Res Public Health, 2021
Qiu Y, Lu W, Guo J, Sun C, Jia P.
europepmc   +1 more source

Special programme of research, development and research training in human reproduction [PDF]

The Special Programme of Research, Development and Research Training in Human Reproduction is one of the few organizations engaged in contraceptive research and development that focusses on the needs of the developing world.
Nassim, Janet
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Reconstructing Multilingual Development Research: Shifting from a Monolingual Bias and Toward a Developmental Systems Framework. [PDF]

Behav Sci (Basel)
Castellana MA, Benitez VL.
europepmc   +1 more source

Aerodynamics support of research instrument development [PDF]

A new velocimetry system is currently being developed at NASA LaRC. The device, known as a Doppler global velocimeter (DGV), can record three velocity components within a plane simultaneously and in near real time. To make measurements the DGV, like many
Miller, L. Scott
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Understanding and redressing imbalances for South-North collaborations in energy and development research. [PDF]

UCL Open Environ
Ali M, Perros T, Yaguma P, Diniz TB, Couto LC, Jatkar H, Cronin J, Fennell P, Szklo A, Mulugetta Y.   +9 more
europepmc   +1 more source