Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
A scoping review of the use of behavioral theories in health professionals' continuing professional development research. [PDF]
BMC Med EducAdlan O +5 more
europepmc +1 more source
A simple method for the application of exogenous phytohormones to the grass leaf base protodermal zone to improve grass leaf epidermis development research. [PDF]
Plant Methods, 2021 Li J, Feng X, Xie J.
europepmc +1 more source
Research and researcher development
Research and researcher development training seminar for ESR ...
openaire +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
The Role of Teachers' Emotions and Their Assessment in Professional Development Research: A Systematic Review. [PDF]
Educ Psychol RevEhlert M, Grunschel C, Koehler F.
europepmc +1 more source
Photovoltaic research and development in Japan [PDF]
The status of the Japanese photovoltaic (PV) R&D activities was surveyed through literature searches, private communications, and site visits in 1982.
Shimada, K.
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Application of machine learning in early childhood development research: a scoping review. [PDF]
BMJ OpenBenson FN +6 more
europepmc +1 more source