Results 111 to 120 of about 1,509,136 (297)

Technology Status and Development Trend of Wind Turbine Generation System

open access: yesKongzhi Yu Xinxi Jishu, 2013
The development status of global wind power generation is illustrated and the status of wind turbine R&D technology in China and the technology gaps between China and foreign countries are analyzed.
ZHANG Xinning
doaj  

Analysis of the development trend of China’s business administration based on time series

open access: yesSHS Web of Conferences, 2016
On the general direction of the economic system, China is in a crucial period of the establishment of the modern enterprise system and reform of the macroeconomic system, and a lot of high-quality business administration talents are required to make ...
Jiang Rui
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Key Technical Progress and Development Trend of Automated Drilling

open access: yesShiyou jixie, 2017
To promote the overall development of automated drilling technology, foreign companies and research groups have increased the research efforts of relevant technology and take the initiative to cooperation and integration.SPE Drilling System Automation ...
Yang Chuanshu, Zhang Haolin, Xiao Li
doaj  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Development of Domestic and Overseas Liner Drilling Technology

open access: yesShiyou jixie, 2018
Liner drilling can effectively address the drilling problems such as narrow drilling boundary, tight hole, well loss and wellbore instability, and reduce drilling time and operating cost, which is especially suitable for deepwater drilling and depleted ...
Wu Jinxia, Zhang Rui
doaj  

Background Paper: LAC Small Island Development States

open access: yes, 2014
Despite the many differences among Caribbean nations, Climate Change (CC) poses a serious threat to them all. Average temperatures in the Region have increased by 0.1° to 0.2°C per decade over the past three decades and rainfall patterns have shifted ...
Inter-American Development Bank
core   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

DEO 2010: Main Messages

open access: yes, 2011
This presentation discusses the most important findings of the Development Effectiveness Overview (DEO) of 2010. The DEO is a reporting instrument of the Development Effectiveness Framework approved in 2008.
Inter-American Development Bank
core   +1 more source

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