Results 171 to 180 of about 17,112,399 (298)

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Research Progress and the Development Trend of the Utilization of Crop Straw Biomass Resources in China. [PDF]

Front Chem, 2022
Yang W, Li X, Zhang Y.
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Development trend analysis of ranolazine, based on bibliometrics. [PDF]

Medicine (Baltimore)
Zhang J, Yan B, Wang J.
europepmc   +1 more source

Spatial connection network characteristics and development trend forecast of natural gas industry's sustainable development resilience in China. [PDF]

Sci Prog, 2023
Zhao Y, Wang D.
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Action Mechanism, Research Progress and Development Trend of High-Temperature Steam Flooding and Profile Control/Flooding Systems. [PDF]

Gels
Liu Y, Bai J, Han X, Wang Q, Zhang H, Wang H, Liu J, Gao Y, Yin X, Liu Z.   +9 more
europepmc   +1 more source

Development trend of primary healthcare after health reform in China: a longitudinal observational study. [PDF]

BMJ Open, 2022
Feng J, Gong Y, Li H, Wu J, Lu Z, Zhang G, Zhou X, Yin X.   +7 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

The global development trend of occupational therapy applied in stroke: A bibliometric study and visualized analysis via VOSviewer and CiteSpace from 2006 to 2025. [PDF]

Medicine (Baltimore)
Liu LX, Wang HH, Dai Y, Lu S, Yu G, Lai QH, Wu M.   +6 more
europepmc   +1 more source