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FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
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The diversification of developmental biology
Studies in History and Philosophy of Science Part C:Studies in History and Philosophy of Biological and Biomedical Sciences, 2015In the 1960s, "developmental biology" became the dominant term to describe some of the research that had previously been included under the rubrics of embryology, growth, morphology, and physiology. As scientific societies formed under this new label, a new discipline took shape.
Nathan Crowe, Michael R Dietrich
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Disability and developmental biology
Development, 2023ABSTRACT Disabled scientists face tremendous barriers to entry into, and progression within, a scientific career, remaining immensely under-represented at every career stage. Disability inclusivity drives in science are increasingly prevalent, but few data are available from the developmental biology community specifically.
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From Developmental Biology to Developmental Toxicology
Annals of the New York Academy of Sciences, 2000Abstract: Progress derived from the human genome project will have tremendous impact on toxicology. Questions concerning genetic susceptibility or resistance to toxic compound exposure and the dissection of the molecular mechanisms involved will be at the forefront of future toxicological research.
BALLING, Rudi, Hrabe de Angelis, M.
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Developmental Biology of Zebrafish
Annals of the New York Academy of Sciences, 2004Abstract: The biology and genetics of zebrafish has become a very popular system in developmental biology especially because of their suitability for genetics and the transparent embryo of this small tropical fish. Studies reported briefly here demonstrate that one can use gene expression in the zebrafish embryo to find new components of important and
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DEVELOPMENTAL BIOLOGY OF HEMATOPOIESIS
Hematology/Oncology Clinics of North America, 1997Hematopoietic stem cells are at the top of a hierarchy that regulates the generation of a vast repertoire of blood cells during the lifetime of a vertebrate. Recent experiments, using a vast variety of embryonic systems, shed new light on the origin of stem cells and the genes that function to regulate and maintain hematopoietic differentiation ...
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The Biology of Developmental Dyslexia
JAMA: The Journal of the American Medical Association, 1992Dyslexia is a relatively common disorder that, when severe, persists into adulthood. New evidence suggests that females are affected nearly as frequently as males. Neuropsychological studies characterize dyslexia as a language disorder that involves phonological deficits in particular.
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The developmental biology of cementum
The International Journal of Developmental Biology, 2001In conclusion, we have reviewed an extensive literature on early cementogenesis and performed a detailed morphological and molecular analysis to illustrate and verify key issues in the current debate about epithelial and mesenchymal contributions to root cementum.
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