Results 41 to 50 of about 488,730 (215)
Spatial cancer systems biology resolves heterotypic interactions and identifies disruption of spatial hierarchy as a pathological driver event [PDF]
arXiv, 2023 Spatially annotated single-cell datasets provide unprecedented opportunities to dissect cell-cell communication in development and disease. Heterotypic signaling includes interactions between different cell types and is well established in tissue development and spatial organization.
arxiv
Adamts18 modulates the development of the aortic arch and common carotid artery
iScience, 2021 Summary: Members of a disintegrin and metalloproteinases with thrombospondin motif (ADAMTS) family have been implicated in various vascular diseases. However, their functional roles in early embryonic vascular development are unknown.
Shuai Ye +10 more
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An ATX-LPA6-Gα13-ROCK axis shapes and maintains caudal vein plexus in zebrafish
iScience, 2021 Summary: Lysophosphatidic acid (LPA) is a potential regulator of vascular formation derived from blood. In this study, we utilized zebrafish as a model organism to monitor the blood vessel formation in detail.
Ryohei Okasato +5 more
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Developmental biology of the pancreas [PDF]
Development, 1995 ABSTRACT The pancreas is an organ containing two distinct populations of cells, the exocrine cells that secrete enzymes into the digestive tract, and the endocrine cells that secrete hormones into the bloodstream. It arises from the endoderm as a dorsal and a ventral bud which fuse together to form the single organ.
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Developmental Biology in México
The International Journal of Developmental Biology, 2021 Contemporary scientific endeavor in México emanates from two great public institutions: the Universidad Nacional Autónoma de México (UNAM) and the Instituto Politécnico Nacional (IPN), founded in 1929 and 1936, respectively. Here, the first research institutes and centers dedicated to various scientific areas were created.
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Perspectives on the mathematics of biological patterning and morphogenesis [PDF]
Journal of the Mechanics and Physics of Solids, 99, 192-210, 2017, 2016 A central question in developmental biology is how size and position are determined. The genetic code carries instructions on how to control these properties in order to regulate the pattern and morphology of structures in the developing organism. Transcription and protein translation mechanisms implement these instructions. However, this cannot happen
arxiv +1 more source
Developmental biology of erythropoiesis
Blood Reviews, 1998 A newborn infant represents the culmination of developmental events from conception through organogenesis. Red cells are critically important for survival and growth of the embryo. During development, erythropoiesis occurs in two distinct forms. The first 'primitive' form consists of nucleated erythroblasts that differentiate within the blood vessels ...
James Palis, George B. Segel
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Protocol for isolation and ATAC-seq library construction of zebrafish red blood cells
STAR Protocols, 2022 Summary: Understanding chromatin dynamics in red blood cells (RBCs) is critical for exploring the differentiation process and homeostasis maintenance during erythropoiesis.
Yanyan Ding, Feng Liu
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X-Linked Huwe1 Is Essential for Oocyte Maturation and Preimplantation Embryo Development
iScience, 2020 Summary: HUWE1 is a HECT-domain ubiquitin E3 ligase expressed in various tissues. Although HUWE1 is known to promote degradation of the tumor suppressor p53, given a growing list of its substrates, in vivo functions of HUWE1 remain elusive.
Alaa A. Eisa +11 more
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Non-muscle myosin II drives critical steps of nematocyst morphogenesis
iScience, 2023 Summary: Nematocysts are generated by secretion of proteins into a post-Golgi compartment. They consist of a capsule that elongates into a long tube, which is coiled inside the capsule matrix and expelled during its nano-second discharge deployed for ...
Niharika Garg +12 more
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