Results 51 to 60 of about 580,764 (305)

Co-option of an ancestral peptidase controls developmental patterning in multicellular cyanobacteria

iScience
Summary: Spatial patterning in multicellular organisms is commonly explained by Turing-type reaction-diffusion systems, but the maturation of diffusible inhibitors remains poorly understood.
Xiaomei Xu, Anaïs Scholivet, Stéphanie Champ, Matthieu Bergé, Zulihumaer Yeerkenjiang, Jonas Desjardins, Yann Denis, Badreddine Douzi, Deborah Byrne, Emmanuel Talla, Amel Latifi   +10 more
doaj   +1 more source

Dynamics of cell rounding during detachment

iScience, 2023
Summary: Animal cells undergo repeated shape changes, for example by rounding up and respreading as they divide. Cell rounding can be also observed in interphase cells, for example when cancer cells switch from a mesenchymal to an ameboid mode of cell ...
Agata Nyga, Katarzyna Plak, Martin Kräter, Marta Urbanska, Kyoohyun Kim, Jochen Guck, Buzz Baum   +6 more
doaj   +1 more source

Developmental Biology in México

The International Journal of Developmental Biology, 2021
Contemporary scientific endeavor in México emanates from two great public institutions: the Universidad Nacional Autónoma de México (UNAM) and the Instituto Politécnico Nacional (IPN), founded in 1929 and 1936, respectively. Here, the first research institutes and centers dedicated to various scientific areas were created.
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Generation of a cancer testis antigen mCherry reporter HCT116 colorectal carcinoma cell line

Heliyon, 2018
In the context of cancer immunotherapy, agents that target the immune system to cancer cells need to fulfil two criteria: 1) that they are only expressed on the desired target cell and 2) that they can elicit a potent immunological response.
Jyoti B. Chhetri, Elena Drousioti, José Afonso Guerra-Assunção, Javier Herrero, Steen K.T. Ooi   +4 more
doaj   +1 more source

Developmental biology of erythropoiesis

Blood Reviews, 1998
A newborn infant represents the culmination of developmental events from conception through organogenesis. Red cells are critically important for survival and growth of the embryo. During development, erythropoiesis occurs in two distinct forms. The first 'primitive' form consists of nucleated erythroblasts that differentiate within the blood vessels ...
J, Palis, G B, Segel
openaire   +2 more sources

Celebrating 100 years of Developmental Biology at the Hubrecht Institute

, 2017
This special issue of Developmental Biology is to celebrate the 100th anniversary of the Hubrecht Institute for Developmental Biology and Stem Cell ...
Jeroen den Hertog, Alexander van Oudenaarden, den Hertog, J., van Oudenaarden, Alexander, van Oudenaarden, A., den Hertog, Jeroen   +5 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Sir2D, a Sirtuin family protein, regulates adenylate cyclase A expression through interaction with the MybB transcription factor early in Dictyostelium development upon starvation

Heliyon, 2019
Sirtuin interacts with many regulatory proteins involved in energy homeostasis, DNA repair, cell survival, and lifespan extension. We investigated the functional roles of Sir2D during early Dictyostelium development upon starvation. We found that ectopic
Hideo Taniura, Shuhei Soeda, Tomoko Ohta, Maya Oki, Risako Tsuboi   +4 more
doaj   +1 more source

Loss of miR-29a impairs decidualization of endometrial stromal cells by TET3 mediated demethylation of Col1A1 promoter

iScience, 2021
Summary: A conceptual framework for understanding abnormal endometrial decidualization, with considerable significance for the diagnosis and treatment of abnormal decidualization-related changes in non-receptive endometrium in implantation failure during
Aixia Liu, Mengmeng Jin, Laidi Xie, Mengyu Jing, Ying Zhou, Minyue Tang, Tingting Lin, Dimin Wang   +7 more
doaj   +1 more source