Results 11 to 20 of about 194,620 (266)
Null hypotheses for developmental evolution [PDF]
Development, 2020 ABSTRACT How much evolutionary change in development do we expect? In this Spotlight, we argue that, as developmental biologists, we are in a prime position to contribute to the definition of a null hypothesis for developmental evolution: in other words, a hypothesis for how much developmental evolution we expect to observe over time ...
Samuel H. Church, Cassandra G. Extavour
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Puberty and the Evolution of Developmental Science [PDF]
Journal of Research on Adolescence, 2019 In recent decades, theoretical and methodological advances have operated synergistically to advance understanding of puberty and prompt increasingly comprehensive models that engage with the temporal, psychosocial, and biological dimensions of this maturational milepost.
Carol M. Worthman +2 more
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EVOLUTION AND BIFURCATION OF DEVELOPMENTAL PROGRAMS [PDF]
Evolution, 1982 The idea that development can tell us something about the organization of the diversity of life predates the establishment of Darwinian evolution. For example, Agassiz (1849) presented a very elaborate theory illustrating the parallelism between the hierarchical organization of life (immutable and a reflection of God's plan) and the sequential process ...
G, Oster, P, Alberch
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EVOLUTION OF EVOLVABILITY IN A DEVELOPMENTAL MODEL [PDF]
Evolution, 2008 Evolvability, the ability of populations to adapt, can evolve through changes in the mechanisms determining genetic variation and in the processes of development. Here we construct and evolve a simple developmental model in which the pleiotropic effects of genes can evolve.
Jeremy, Draghi, Günter P, Wagner
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Developmental evolution: This side of paradise [PDF]
Current Biology, 1999 It has long been appreciated that the evolution of snakes involved the loss of limbs and axis elongation, but their developmental basis has been obscure. It has now been shown that alterations in the deployment of Hox genes and an early block in the formation of hindlimb primordia underpin these modifications.
Graham, Anthony, McGonnell, Imelda
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Developmental bias in the evolution of phalanges [PDF]
Proceedings of the National Academy of Sciences, 2013 Significance It has long been proposed that rules stemming from the mechanisms used during development can constrain the range of evolvable variations in a given form, but few empirical examples are known. We have focused on developmental processes determining proportions of phalanx size along individual digits (fingers/toes) of ...
Kathryn D, Kavanagh +6 more
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A topological look into the evolution of developmental programs [PDF]
Biophysical Journal, 2021 Rapid advance of experimental techniques provides an unprecedented in-depth view into complex developmental processes. Still, little is known on how the complexity of multicellular organisms evolved by elaborating developmental programs and inventing new cell types.
Somya Mani, Tsvi Tlusty
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Rpn11-mediated ubiquitin processing in an ancestral archaeal ubiquitination system
Nature Communications, 2018 Ubiquitin modification also occurs in archaea. Here, the authors characterize an archaeal ancestral ubiquitination system, present the crystal structure of the archaeal deubiquitinase Rpn11 from Caldiarchaeum subterraneum bound to ubiquitin and provide ...
Adrian C. D. Fuchs +4 more
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A vocabulary of ancient peptides at the origin of folded proteins
eLife, 2015 The seemingly limitless diversity of proteins in nature arose from only a few thousand domain prototypes, but the origin of these themselves has remained unclear.
Vikram Alva +2 more
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eLife, 2019 Sequential developmental events, starting from the moment of fertilization, are crucial for the acquisition of animal body plan. Subtle modifications in such early events are likely to have major impacts in later morphogenesis, bringing along ...
Jorge Torres-Paz +2 more
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