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Evolution and developmental biology in The Netherlands [PDF]
Contributions to Zoology, 2002 I have long maintained that in the unfolding of exciting lines of research, seldom can one plan how to achieve a cooperative program. “Planned science,” more often than not, is forced science and not particularly productive. Far more significant is the role of serendipity in defining an exciting and innovative line of research, i.e., a truly ...
openaire +3 more sources
Dogs distinguish human intentional and unintentional action
Scientific Reports, 2021 When dogs interact with humans, they often show appropriate reactions to human intentional action. But it is unclear from these everyday observations whether the dogs simply respond to the action outcomes or whether they are able to discriminate between ...
Britta Schünemann +4 more
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BMC Biology, 2019 Background The spatial organization of the mammalian genome relies upon the formation of chromatin domains of various scales. At the level of gene regulation in cis, collections of enhancer sequences define large regulatory landscapes that usually match ...
Eddie Rodríguez-Carballo +4 more
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Replacing the phthalimide core in thalidomide with benzotriazole
Journal of Enzyme Inhibition and Medicinal Chemistry, 2022 The advent of proteolysis-targeting chimaeras (PROTACs) mandates that new ligands for the recruitment of E3 ligases are discovered. The traditional immunomodulatory drugs (IMiDs) such as thalidomide and its analogues (all based on the phthalimide ...
Mikhail Krasavin +8 more
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F1000Research, 2016 Human language emerged abruptly. Diverse body forms evolved suddenly. Seed-bearing plants spread rapidly. How do complex evolutionary innovations arise so quickly? Resolving alternative claims remains difficult.
Steven A. Frank
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Diversity, 2022 Russia has a number of historical foci of zoonotic anthropogenic diseases. In Central Russia, the Republic of Mordovia is one of such areas, a region being known to have foci of haemorrhagic fever with renal syndrome (HFRS) and tularemia.
Alexey Andreychev +4 more
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Parallel evolution of amphioxus and vertebrate small-scale gene duplications
Genome Biology, 2022 Background Amphioxus are non-vertebrate chordates characterized by a slow morphological and molecular evolution. They share the basic chordate body-plan and genome organization with vertebrates but lack their 2R whole-genome duplications and their ...
Marina Brasó-Vives +13 more
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F1000Research, 2017 Despite the progress that has been made in many other aspects of data visualisation, phylogenies are still represented in much the same way as they first were by Darwin.
William D. Pearse
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nQuire: a statistical framework for ploidy estimation using next generation sequencing
BMC Bioinformatics, 2018 Background Intraspecific variation in ploidy occurs in a wide range of species including pathogenic and nonpathogenic eukaryotes such as yeasts and oomycetes. Ploidy can be inferred indirectly - without measuring DNA content - from experiments using next-
Clemens L. Weiß +4 more
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Evolutionary loss of melanogenesis in the tunicate Molgula occulta
EvoDevo, 2017 Background Analyzing close species with diverse developmental modes is instrumental for investigating the evolutionary significance of physiological, anatomical and behavioral features at a molecular level.
Claudia Racioppi +8 more
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