Results 201 to 210 of about 445,854 (255)

Genetic testing and analysis of 1024 children with global developmental delay or intellectual disability: a single-center cohort study. [PDF]

Eur J Pediatr
Wang B, Ji X, Wu F, Shen M, Zheng P, Feng S, Wu H, Li S, Liu A, Xie L, Zhang X, Chen Q.   +11 more
europepmc   +1 more source

Dissecting the molecular mechanism of developmental macular dystrophies

, 2020
openaire   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Multiplexed CRISPR/Cas9 Editing of Tumor Suppressor Genes in the Mouse Endometrium Recapitulates High-Risk Endometrial Carcinoma

Cancer Communications
Maria Vidal-Sabanés, Raúl Navaridas, Núria Bonifaci, Ada Gay-Rua, Damià Ortega-Peinado, Joaquim Egea, Mario Encinas, Xavier Matias-Guiu, David Llobet-Navas, Xavier Dolcet   +9 more
doaj   +1 more source

Microglia in autism spectrum disorder: heterogeneity, immunometabolism, and synapse-related pathways. [PDF]

Front Immunol
Lian A, He M, Zhang H, Yang Y.
europepmc   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Identification of genes controlling grain size in barley through RNA-seq and weighted gene co-expression network analysis. [PDF]

Funct Integr Genomics
Xie R, Wang Y, Yang M, Zhou J, Yao Y, Cui Y, Li X, Ding B, Yao X, Wu K.   +9 more
europepmc   +1 more source

Cannabidiol in Developmental Epilepsy: Organoid-Guided Precision Medicine Across Critical Neurodevelopmental Windows. [PDF]

Int J Mol Sci
Joo J, Yang WS, Koh HJ.
europepmc   +1 more source

Sex as a biological variable in amblyopia: implications for developmental plasticity and treatment. [PDF]

Front Neurosci
Murphy KM, Monteiro L, Panday M, Barone N.   +3 more
europepmc   +1 more source