Results 261 to 270 of about 7,143,981 (292)
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Molecular and developmental mechanisms of congenital heart valve disease
Birth Defects Research Part A: Clinical and Molecular Teratology, 2011AbstractCongenital heart disease occurs in approximately 1% of all live births and includes structural abnormalities of the heart valves. However, this statistic underestimates congenital valve lesions, such as bicuspic aortic valve (BAV) and mitral valve prolapse (MVP), that typically become apparent later in life as progressive valve dysfunction and ...
Joy, Lincoln, Katherine E, Yutzey
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MOLECULAR MECHANISMS IN DEVELOPMENTAL BIOLOGY
Cell Biology International, 1996AbstractSome general molecular mechanisms underlying development are described. Namely: those involved in the differentiation of the R7 receptor inDrosophilaembryonic retina; those involved in the determination of embryonic axes and in polar cell differentiation, inDrosophila; those involved in the determination of the AB and P cell lineage and in ...
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Genomic imprinting: developmental significance and molecular mechanism
Current Opinion in Genetics & Development, 1991Imprinting results in the preferential expression of either the maternal or the paternal allele of certain genes, and has a critical influence on the regulation of mammalian development. The identification of specific imprinted chromosomal regions and genes is being used to unravel the molecular mechanism of imprinting and the developmental ...
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Environmental antiandrogens: developmental effects, molecular mechanisms, and clinical implications
Journal of Molecular Medicine, 1997Industrial chemicals and environmental pollutants can disrupt reproductive development in wildlife and humans by mimicking or inhibiting the action of the gonadal steroid hormones, estradiol and testosterone. The toxicity of these so-called environmental endocrine disruptors is especially insidious during sex differentiation and development due to the ...
W R, Kelce, E M, Wilson
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Molecular Mechanisms of Crude Oil Developmental Toxicity in Fish
Archives of Environmental Contamination and Toxicology, 2017With major oil spills in Korea, the United States, and China in the past decade, there has been a dramatic increase in the number of studies characterizing the developmental toxicity of crude oil and its associated polycyclic aromatic compounds (PACs).
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Developmental Effects and Molecular Mechanisms of Environmental Antiandrogens
1998Industrial chemicals and environmental pollutants can disrupt reproductive development in wildlife and humans by altering the synthesis, transport, action, or elimination of gonadal steroid hormones. Steroid hormones control fundamental events in embryonic development and sex differentiation by binding to their cognate nuclear receptors, which act as ...
William R. Kelce, Elizabeth M. Wilson
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Molecular Mechanisms of Human Embryogenesis: Developmental Pathogenesis of Renal Tract Malformations
Pediatric and Developmental Pathology, 2002The focus of this review is the normal and abnormal development of the kidney and lower urinary tract; for convenience, we will refer to the whole system as the renal tract. The content represents a convergence among the clinical disciplines of histopathology, nephrology, and urology as well the basic sciences of developmental biology and molecular ...
Adrian S, Woolf, Paul J D, Winyard
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Physiology & Behavior, 2004
Postnatal development in most mammals is accompanied by the acquisition of controls of ingestion. In rodents, the initial and default controller appears to be gastric stretch. In the second week of life, rat pups acquire the ability to sense the presence of nutrients within the gut and appropriately modulate ingestion.
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Postnatal development in most mammals is accompanied by the acquisition of controls of ingestion. In rodents, the initial and default controller appears to be gastric stretch. In the second week of life, rat pups acquire the ability to sense the presence of nutrients within the gut and appropriately modulate ingestion.
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Elucidating the molecular mechanisms of developmental timing in mammals
Die Embryonalentwicklung von einer einzelnen Zelle zu einem ausgewachsenen Organismus verläuft bei Säugetieren nach einem strengen Muster, doch die Geschwindigkeit dieser Ereignisse, die Entwicklungszeitskala, ist bei jeder Art einzigartig und variiert erheblich untereinander.openaire +1 more source
[Molecular mechanisms of environmental estrogens on reproductive and developmental toxicity].
Wei sheng yan jiu = Journal of hygiene research, 2003It has been shown that numerous natural and synthetic chemicals with estrogenic activities are reproductive or developmental toxic factors in humans or animals by epidemiological investigations and animal experiments. The mechanisms of toxicity, however, are very complicated, especially the molecular mechanisms.
Dingxin, Long, Yong, Li, Feng, Chen
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