Results 31 to 40 of about 134,836 (257)

Developmental Plasticity of Inhibitory Circuitry [PDF]

open access: yesThe Journal of Neuroscience, 2006
In 1949, Donald Hebb proposed a mechanism for use-dependent synaptic plasticity, suggesting that input neurons that reliably activate their postsynaptic target will strengthen their connections ([Hebb, 1949][1]).
Sarah L, Pallas   +7 more
openaire   +2 more sources

Developmental plasticity of CNS microglia [PDF]

open access: yesProceedings of the National Academy of Sciences, 2001
Microglia arise from CD45 + bone marrow precursors that colonize the fetal brain and play a key role in central nervous system inflammatory conditions. We report that parenchymal microglia are uncommitted myeloid progenitors of immature dendritic cells and macrophages by several criteria,
L, Santambrogio   +8 more
openaire   +2 more sources

RGS9‐2 rescues dopamine D2 receptor levels and signaling in DYT1 dystonia mouse models

open access: yesEMBO Molecular Medicine, 2018
Dopamine D2 receptor signaling is central for striatal function and movement, while abnormal activity is associated with neurological disorders including the severe early‐onset DYT1 dystonia.
Paola Bonsi   +16 more
doaj   +1 more source

Gestational Hypoxia and Developmental Plasticity [PDF]

open access: yesPhysiological Reviews, 2018
Hypoxia is one of the most common and severe challenges to the maintenance of homeostasis. Oxygen sensing is a property of all tissues, and the response to hypoxia is multidimensional involving complicated intracellular networks concerned with the transduction of hypoxia-induced responses.
Charles A, Ducsay   +5 more
openaire   +2 more sources

Physiological mechanisms of adaptive developmental plasticity in Rana temporaria island populations

open access: yesBMC Evolutionary Biology, 2017
Background Adaptive plasticity is essential for many species to cope with environmental heterogeneity. In particular, developmental plasticity allows organisms with complex life cycles to adaptively adjust the timing of ontogenetic switch points. Size at
Pablo Burraco   +3 more
doaj   +1 more source

Developmental phenotypic plasticity in a marsupial [PDF]

open access: yesJournal of Experimental Biology, 2012
SUMMARY Climate change is likely to substantially affect the distribution ranges of species. However, little is known about how different mammalian taxa respond morphologically and physiologically to a rapid change of climate. Our objective was to provide the first quantitative data on the effect of continuous cold exposure during ...
Riek, Alexander, Geiser, Fritz
openaire   +3 more sources

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi   +9 more
wiley   +1 more source

Developmental defects in planarian hatchlings (Platyhelminthes: Rhabditophora) [PDF]

open access: yesZoologia (Curitiba)
Developmental plasticity of the planarians is well-illustrated by whole-body regeneration from any tissue fragments and body size scaling regulated by food intake.
Xiaoting Dai   +3 more
doaj   +1 more source

Categorizing experience-based foraging plasticity in mites: age dependency, primacy effects and memory persistence [PDF]

open access: yesRoyal Society Open Science, 2018
Behavioural plasticity can be categorized into activational (also termed contextual) and developmental plasticity. Activational plasticity allows immediate contextual behavioural changes, whereas developmental plasticity is characterized by time-lagged ...
Peter Schausberger   +3 more
doaj   +1 more source

Intertwined Signaling Pathways Governing Tooth Development: A Give-and-Take Between Canonical Wnt and Shh

open access: yesFrontiers in Cell and Developmental Biology, 2021
Teeth play essential roles in life. Their development relies on reciprocal interactions between the ectoderm-derived dental epithelium and the underlying neural crest-originated mesenchyme.
Florian Hermans   +5 more
doaj   +1 more source

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