Application of Developmental Regulators for Enhancing Plant Regeneration and Genetic Transformation [PDF]
PlantsEstablishing plant regeneration systems and efficient genetic transformation techniques plays a crucial role in plant functional genomics research and the development of new crop varieties.
Pingjun Xu +9 more
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Topological isolation of developmental regulators in mammalian genomes [PDF]
Nature Communications, 2021 The phenotypic consequence of 3D genome boundary disruption on developmental processes remains insufficiently understood. Here, the authors show that perturbation of a SOX17 boundary in human pluripotent stem cells interferes with proper differentiation ...
Hua-Jun Wu +6 more
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Functional Mechanisms and the Application of Developmental Regulators for Improving Genetic Transformation in Plants [PDF]
PlantsEnhancing the genetic transformation efficiency of major crops remains a significant challenge, primarily due to their suboptimal regeneration efficiency.
Yilin Jiang, Siyuan Liu, Xueli An
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Single cell transcriptome analysis of developing arcuate nucleus neurons uncovers their key developmental regulators [PDF]
Nature Communications, 2019 Despite the crucial physiological processes governed by neurons in the hypothalamic arcuate nucleus (ARC), the developmental pathways and regulators for ARC neurons remain understudied.
Christian Huisman +9 more
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Positional Dynamics and Glycosomal Recruitment of Developmental Regulators during Trypanosome Differentiation [PDF]
mBio, 2019 Glycosomes are peroxisome-related organelles that compartmentalize the glycolytic enzymes in kinetoplastid parasites. These organelles are developmentally regulated in their number and composition, allowing metabolic adaptation to the parasite’s needs in
Balázs Szöőr +7 more
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Ep400 deficiency in Schwann cells causes persistent expression of early developmental regulators and peripheral neuropathy [PDF]
Nature Communications, 2019 The Ep400 chromatin remodeler determines genomic distribution of variant histones. In the current study, the authors show that loss of Ep400 in Schwann cells leads to aberrant expression of developmental regulators, and a peripheral neuropathy phenotype.
Franziska Fröb +8 more
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Sex biased expression and co-expression networks in development, using the hymenopteran Nasonia vitripennis. [PDF]
PLoS Genetics, 2020 Sexual dimorphism requires regulation of gene expression in developing organisms. These developmental differences are caused by differential expression of genes and isoforms.
Alfredo Rago +2 more
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Nature Communications, 2021 Trypanosoma brucei undergoes developmental steps during host infection. Here, using oligopeptide-induced differentiation in vitro, authors model replicative ‘slender’ to transmissible ‘stumpy’ bloodstream forms and identify developmental and cell cycle ...
Emma M. Briggs +4 more
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Cyclin E and Cdk2 control GLD-1, the mitosis/meiosis decision, and germline stem cells in Caenorhabditis elegans. [PDF]
PLoS Genetics, 2011 Coordination of the cell cycle with developmental events is crucial for generation of tissues during development and their maintenance in adults. Defects in that coordination can shift the balance of cell fates with devastating clinical effects.
Johan Jeong +2 more
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The effect of developmental stages of corm, type of medium and plant growth regulators in callus induction of Crocus sativus L. [PDF]
Journal of Horticulture and Postharvest Research, 2021 Purpose: The efficiency of callus induction as source of bioactive compound is a critical step in the cell suspension culture for commercial production of important secondary metabolites.
Seyed Mahdi Ziaratnia, Somayeh Amini
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