F1000Research, 2019 Seed development is a complex process and consists of two phases: embryo morphogenesis and seed maturation. LEAFY COTYLEDON (LEC) transcription factors, first discovered in Arabidopsis thaliana several decades ago, are master regulators of seed ...
De Niu, Yuehui He
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Conserved RY-repeats mediate transactivation of seed-specific promoters by the developmental regulator PvALF [PDF]
, 1997 Andrew J. Bobb
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Molecular Oncology, EarlyView.TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam +9 more
wiley +1 more source
Developmental regulation of Tbx5 in zebrafish embryogenesis
Mechanisms of Development, 2000 T-box (tbx) genes constitute a large family of transcriptional regulators involved in developmental patterning processes. In tetrapods, tbx5 has been implicated in specifying forelimb type identity. Here, we report the cloning of the zebrafish tbx5.1 gene and characterise its expression during zebrafish embryogenesis and early larval development of ...
Gerrit Begemann, Philip W. Ingham
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Efficient genetic transformation and CRISPR/Cas9-mediated genome editing of watermelon assisted by genes encoding developmental regulators. [PDF]
J Zhejiang Univ Sci B, 2022 Pan W +5 more
europepmc +1 more source
A negative regulator linking chromosome segregation to developmental transcription in Bacillus subtilis [PDF]
, 1998 Marguerite A. Cervin +5 more
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Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
Molecular Oncology, EarlyView.CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak +14 more
wiley +1 more source
H3K4me2 ChIP-Seq reveals the epigenetic landscape during mushroom formation and novel developmental regulators of Schizophyllum commune. [PDF]
Sci Rep, 2021 Vonk PJ, Ohm RA.
europepmc +1 more source
Interactions of the developmental regulator ABI3 with proteins identified from developing Arabidopsis seeds [PDF]
, 2000 Smita Kurup +2 more
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Molecular Oncology, EarlyView.This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini +10 more
wiley +1 more source