Results 161 to 170 of about 334,033 (329)

EST analysis in Ginkgo biloba: an assessment of conserved developmental regulators and gymnosperm specific genes [PDF]

, 2005
Eric D. Brenner, Manpreet S. Katari, Dennis W. Stevenson, Stephen Rudd, Andrew W. Douglas, Walter N. Moss, Richard W Twigg, Suzan J Runko, Giulia M. Stellari, W. Richard McCombie, Gloria M. Coruzzi   +10 more
openalex   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Fluffy, the major regulator of conidiation in Neurospora crassa, directly activates a developmentally regulated hydrophobin gene [PDF]

, 2005
Panan Rerngsamran, Michael Murphy, Sharon A. Doyle, Daniel J. Ebbole   +3 more
openalex   +1 more source

Time, the final frontier

Molecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain, Michal Dibus, Omkar Joshi, Guillaume Jacquemet   +3 more
wiley   +1 more source

Developmental gene regulatory network architecture across 500 million years of echinoderm evolution [PDF]

, 2003
Evolutionary change in morphological features must depend on architectural reorganization of developmental gene regulatory networks (GRNs), just as true conservation of morphological features must imply retention of ancestral developmental GRN features ...
Cameron, R. Andrew, Davidson, Eric H., Hinman, Veronica F., Nguyen, Albert T.   +3 more
core  

Interactions of juvenile hormone, 20-hydroxyecdysone, developmental genes, and miRNAs during pupal development in Apis mellifera

Scientific Reports
Insect development is primarily controlled by juvenile hormone (JH) and 20-hydroxyecdysone (20E), which regulate gene cascades leading to changes in phenotype, physiology, and behavior.
T. S. Depintor, F. C. P. Freitas, N. Hernandes, F. M. F. Nunes, Z. L. P. Simões   +4 more
doaj   +1 more source

Evolution of vascular plants through redeployment of ancient developmental regulators. [PDF]

Proc Natl Acad Sci U S A, 2020
Lu KJ, van 't Wout Hofland N, Mor E, Mutte S, Abrahams P, Kato H, Vandepoele K, Weijers D, De Rybel B.   +8 more
europepmc   +1 more source

Environmental and developmental signals modulate proline homeostasis: evidence for a negative transcriptional regulator.

, 1996
Nathalie Verbruggen, Xue Jun Hua, Mike May, Marc Van Montagu   +3 more
openalex   +1 more source

The Caenorhabditis elegans Heterochronic Regulator LIN-14 Is a Novel Transcription Factor That Controls the Developmental Timing of Transcription from the Insulin/Insulin-Like Growth Factor Gene ins-33 by Direct DNA Binding [PDF]

, 2005
Marta Hristova, Darcy Birse, Hong Yang, Victor Ambros   +3 more
openalex   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source