Developmental regulators FlbE/D orchestrate the polarity site-to-nucleus dynamics of the fungal bZIP transcription factor FlbB. [PDF]
Otamendi A +5 more
europepmc +1 more source
Characterization of
Karolina A. Akinosoglou +8 more
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Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi +12 more
wiley +1 more source
Bradysia (Sciara) coprophila larvae up-regulate DNA repair pathways and down-regulate developmental regulators in response to ionizing radiation. [PDF]
Urban JM +8 more
europepmc +1 more source
Altered expression of developmental regulators of parvalbumin and somatostatin neurons in the prefrontal cortex in schizophrenia. [PDF]
Volk DW, Edelson JR, Lewis DA.
europepmc +1 more source
The developmental selector AS1 is an evolutionarily conserved regulator of the plant immune response
Pedro Luiz Nurmberg +6 more
openalex +1 more source
Six1 is a key regulator of the developmental and evolutionary architecture of sensory neurons in craniates [PDF]
Hiroshi Yajima +8 more
openalex +1 more source
Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza +3 more
wiley +1 more source
MEF2 transcription factors: developmental regulators and emerging cancer genes. [PDF]
Pon JR, Marra MA.
europepmc +1 more source

