Results 11 to 20 of about 165,041 (290)
Toward Artificial Developmental Regulators [PDF]
A polyamide-peptide conjugate is designed which recruits sequence specifically the developmental regulator Exd to a cognate DNA site. In particular, an eight-ring hairpin polyamide (Im-Im-Py(C3H6NHR)-Py-gamma-Im-Py-Py-Py-beta-Dp) with a heptapeptide (R = Ac-Phe-Tyr-Pro-Trp-Met-Lys-Gly-) attached on a central ring was shown to induce cooperative binding
Hans‐Dieter Arndt +5 more
openalex +6 more sources
microRNAs as Developmental Regulators. [PDF]
The field of miRNA biology is relatively young, but its impact on our understanding of the regulation of a wide array of cell functions is far-reaching. The importance of miRNAs in development has become nearly ubiquitous, with miRNAs contributing to development of most cells and organs.
Ivey KN, Srivastava D.
europepmc +6 more sources
Vascular Regulation of Developmental Neurogenesis
Evolutionary studies indicate that the nervous system evolved prior to the vascular system, but the increasing complexity of organisms prompted the vascular system to emerge in order to meet the growing demand for oxygen and nutrient supply. In recent years, it has become apparent that the symbiotic communication between the nervous and the vascular ...
Johanna Vogenstahl +7 more
openaire +3 more sources
MicroRNA-driven developmental remodeling in the brain distinguishes humans from other primates. [PDF]
While multiple studies have reported the accelerated evolution of brain gene expression in the human lineage, the mechanisms underlying such changes are unknown. Here, we address this issue from a developmental perspective, by analyzing mRNA and microRNA
Mehmet Somel +14 more
doaj +1 more source
The effect of developmental stages of corm, type of medium and plant growth regulators in callus induction of Crocus sativus L. [PDF]
Purpose: The efficiency of callus induction as source of bioactive compound is a critical step in the cell suspension culture for commercial production of important secondary metabolites.
Seyed Mahdi Ziaratnia, Somayeh Amini
doaj +1 more source
The engineering of developmental regulation [PDF]
It is fast becoming clear that, to understand the complexity of biological systems, it is not enough just to have mechanistic explanations for how things happen. We also need explanations for why things are there, i.e. what it is about particular states of affairs that enabled them to have been selected for.
openaire +3 more sources
Different Preclimacteric Events in Apple Cultivars with Modified Ripening Physiology
“Anna” is an early season apple cultivar exhibiting a fast softening and juiciness loss during storage, in comparison to two mid-late season cultivars “Galaxy” and “GD.” The poor storage capacity of “Anna” was correlated with high lipid oxidation-related
Vikram Singh +2 more
doaj +1 more source
PlantLayout pipeline to model tissue patterning
To study the mechanisms underlying developmental pattern formation in a tissue, one needs to analyze the dynamics of the regulators in time and space across the tissue of a specific architecture. This problem is essential for the developmental regulators
M. S. Savina, V. V. Mironova
doaj +1 more source
Highlighting reactive oxygen species as multitaskers in root development
Summary: Reactive oxygen species (ROS) are naturally produced by several redox reactions during plant regular metabolism such as photosynthesis and respiration.
Ali Eljebbawi +3 more
doaj +1 more source
A High-Throughput Small Molecule Screen for C. elegans Linker Cell Death Inhibitors. [PDF]
Programmed cell death is a ubiquitous process in metazoan development. Apoptosis, one cell death form, has been studied extensively. However, mutations inactivating key mammalian apoptosis regulators do not block most developmental cell culling ...
Andrew R Schwendeman, Shai Shaham
doaj +1 more source

