Results 301 to 310 of about 357,386 (324)

Dynamic Developmental Gene Regulation

Science's STKE, 2007
Gene regulatory networks control metazoan development and determine which transcription factors will regulate which regulatory genes. However, development is a dynamic process that is driven by continuous change in time and space. Smith et al .
openaire   +2 more sources

Evolution of Developmental Regulation

The American Naturalist, 1989
Our knowledge of the evolution of gene regulation is still rudimentary. From the few well-studied paradigms, it is apparent that regulatory systems are diverse and complex. Consequently, broad generalizations should not be made at this time. Rather, detailed molecular, developmental, and phylogenetic data are needed to elucidate simultaneously the ...
openaire   +1 more source

Developmentally regulated glycosylation of dopamine transporter

Developmental Brain Research, 1994
The dopamine transporter (DAT) in rat striatum was examined during postnatal development and aging after photolabeling with [125I]DEEP. The DAT-[125I]DEEP protein complex from adult rats (2 months) appeared as a broad diffuse band in SDS-PAGE gels with average apparent molecular mass of about 80,000 Da as previously found.
A P, Patel, C, Cerruti, R A, Vaughan, M J, Kuhar   +3 more
openaire   +2 more sources

Developmental regulation of erythropoietin and erythropoiesis

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 1997
It is well established that erythropoiesis occurs first in the yolk sac, then in the liver, subsequently moving to the bone marrow and, in rodents, the spleen during development. The origin of the erythropoietic precursors and some factors suggested to be important for the changing location of erythropoiesis are discussed in this review. Until recently,
Moritz, KM, Lim, GB, Wintour, EM
openaire   +2 more sources

Developmental Regulation of Lung Liquid Transport

Annual Review of Physiology, 2004
▪ Abstract  The developing distal lung epithelium displays an evolving liquid transport phenotype, reflecting a changing and dynamic balance between Cl−ion secretion and Na+ion absorption, which in turn reflects changing functional requirements. Thus in the fetus, Cl−-driven liquid secretion predominates throughout gestation and generates a distending ...
Richard E, Olver, Dafydd V, Walters, Stuart, M Wilson   +2 more
openaire   +2 more sources

The origins of developmental gene regulation

Evolution & Development, 2017
SUMMARYThe leap from simple unicellularity to complex multicellularity remains one of life's major enigmas. The origins of metazoan developmental gene regulatory mechanisms are sought by analyzing gene regulation in extant eumetazoans, sponges, and unicellular organisms.
openaire   +2 more sources

Developmental Regulation of Elastin Gene Expression

Critical Reviews™ in Eukaryotic Gene Expression, 1997
Developmental regulation of elastin gene expression appears to be exerted primarily at the transcriptional level. Although the elastin gene promoter possesses features of "housekeeping" genes, these characteristics do not preclude transcriptional regulation as shown with a number of other gene promoters of this class.
S, Perrin, J A, Foster
openaire   +2 more sources

Perinatal Developmental Origins of Self-Regulation

2014
The developmental origins of behavior, health, and disease (DOBHaD) hypothesis examines the short- and long-term effects of environmental conditions early in life on phenotypic variations in behavior, health, and disease. The prenatal and early postnatal periods are times of great opportunity and considerable risk, and their influence can extend over a
Henrichs, J., Van Den Bergh, B.R.H.
openaire   +2 more sources

Developmental Regulation of the Immune System

Seminars in Perinatology, 2006
Term newborns have a higher frequency of microbial infections than older children and adults. Extremely premature newborns (
openaire   +2 more sources

Developmental regulation of the growth plate

Nature, 2003
Vertebrates do not look like jellyfish because the bones of their skeletons are levers that allow movement and protect vital organs. Bones come in an enormous variety of shapes and sizes to accomplish these goals, but, with few exceptions, use one process--endochondral bone formation--to generate the skeleton.
openaire   +2 more sources