Results 31 to 40 of about 334,033 (329)

Differential Hox expression in murine embryonic stem cell models of normal and malignant hematopoiesis [PDF]

, 2011
The Hox family are master transcriptional regulators of developmental processes, including hematopoiesis. The Hox regulators, caudal homeobox factors (Cdx1-4), and Meis1, along with several individual Hox proteins, are implicated in stem cell expansion ...
Alexander Thompson, Belotti D, Buske C, Deschamps J, Edwina Dobbin, Glenda J. Dickson, Helen Wheadon, Joanne M. Ramsey, Lawrence HJ, Pamela M. Corrigan, Robin W. Freeburn   +10 more
core   +1 more source

Identification and stage-specific association with the translational apparatus of TbZFP3, a CCCH protein that promotes trypanosome life-cycle development [PDF]

, 2006
The post-transcriptional control of gene expression is becoming increasingly important in the understanding of regulated events in eukaryotic cells. The parasitic kinetoplastids have a unique reliance on such processes, because their genome is organized ...
Athina Paterou, Barreau, Berriman, Biebinger, Blackshear, Brecht, Breeden, Caro, Chekulaeva, Chen, Clayton, Gao, Gietz, Guedes, Gunzl, Hammarton, Hammarton, Hendriks, Hendriks, Hollenberg, Hudson, Ivens, Katelyn Fenn, Keene, Keith Matthews, Lai, Matthews, Matthews, Moore, Morking, Ogura, Paul Craddy, Pegine Walrad, Priest, Reese, Rudenko, Schmitz, Sutton, Tabara, Tacahashi, Tenenhaus, Tielens, Tu, Tu, van Deursen, van Weelden, Wentz-Hunter, Wickens, Ziegelbauer   +48 more
core   +1 more source

The effect of endo- and exogenous factors on growth and maturation of oilseed rape (Brassica napus cv. Jet Neuf) siliques cultured in vitro

Acta Societatis Botanicorum Poloniae, 2014
The effect of developmental stage of siliques, growth regulators, agar and sucrose concentrations in the medium was investigated on the morphogenesis of the silliques and seed maturation.
Lucyna Drozdowska, Małgorzata Ulanowska, Janina Rogozińska   +2 more
doaj   +1 more source

Transcriptomic signatures of neuronal differentiation and their association with risk genes for autism spectrum and related neuropsychiatric disorders. [PDF]

, 2016
Genes for autism spectrum disorders (ASDs) are also implicated in fragile X syndrome (FXS), intellectual disabilities (ID) or schizophrenia (SCZ), and converge on neuronal function and differentiation. The SH-SY5Y neuroblastoma cell line, the most widely
Chiocchetti, AG, Cocchi, E, de la Torre-Ubieta, L, Freitag, CM, Fulda, S, Geschwind, DH, Haslinger, D, Lindlar, S, Rothämel, T, Stein, JL, Waltes, R   +10 more
core   +1 more source

Cell-fate transition and determination analysis of mouse male germ cells throughout development

Nature Communications, 2021
The full-term developmental profile of male germ cells remains undefined. Here, the authors use single-cell sequencing to investigate the transcriptome landscapes of mouse male germ cells throughout development and find several critical regulators for ...
Jiexiang Zhao, Ping Lu, Cong Wan, Yaping Huang, Manman Cui, Xinyan Yang, Yuqiong Hu, Yi Zheng, Ji Dong, Mei Wang, Shu Zhang, Zhaoting Liu, Shuhui Bian, Xiaoman Wang, Rui Wang, Shaofang Ren, Dazhuang Wang, Zhaokai Yao, Gang Chang, Fuchou Tang, Xiao-Yang Zhao   +20 more
doaj   +1 more source

iNID: An Analytical Framework for Identifying Network Models for Interplays among Developmental Signaling in Arabidopsis [PDF]

, 2019
Integration of internal and external cues into developmental programs is indispensable for growth and development of plants, which involve complex interplays among signaling pathways activated by the internal and external factors (IEFs).
Cho, YH, Choi, D, Choi, J, Hwang, D, Hwang, I, Kang, B, Lee, S   +6 more
core   +1 more source

Development and regulation of chloride homeostasis in the central nervous system

Frontiers in Cellular Neuroscience, 2015
GABA (γ-aminobutyric acid) is the main inhibitory neurotransmitter of the mature central nervous system. The developmental switch of GABAergic transmission from excitation to inhibition is induced by changes in Cl- gradients, which are generated by ...
Miho eWatanabe, Atsuo eFukuda
doaj   +1 more source

DevA, a GntR-like transcriptional regulator required for development in streptomyces coelicolor [PDF]

, 2006
The gram-positive filamentous bacterium Streptomyces coelicolor has a complex developmental cycle with three distinct phases: growth of the substrate mycelium, development of reproductive structures called aerial hyphae, and differentiation of these ...
Buttner, Mark J., Findlay, Kim C., Fowler, Kay, Hoskisson, Paul A., Rigali, Sebastien   +4 more
core   +2 more sources

Review and Validation of Plant Gene Function Research Methods Bypassing Tissue Culture

Agronomy
The genetic transformation of plants has provided fundamental insights into plant biology. However, the genetic transformation systems for most horticultural plants remain incomplete.
Huanghuang Jiang, Suya Huang, Jiayi Wang, Deming Sun, Min Wang, Su Lin, Jinhua Liu, Kai Xu, Bei Liu, Haijie Ma   +9 more
doaj   +1 more source

High content image analysis identifies novel regulators of synaptogenesis in a high-throughput RNAi screen of primary neurons.

PLoS ONE, 2014
The formation of synapses, the specialized points of chemical communication between neurons, is a highly regulated developmental process fundamental to establishing normal brain circuitry.
Thomas J F Nieland, David J Logan, Jessica Saulnier, Daniel Lam, Caroline Johnson, David E Root, Anne E Carpenter, Bernardo L Sabatini   +7 more
doaj   +1 more source