Results 31 to 40 of about 165,041 (290)

A Systems Biology Approach to Identify Essential Epigenetic Regulators for Specific Biological Processes in Plants

open access: yesPlants, 2021
Upon sensing developmental or environmental cues, epigenetic regulators transform the chromatin landscape of a network of genes to modulate their expression and dictate adequate cellular and organismal responses.
Rachel M. McCoy   +5 more
doaj   +1 more source

Identification of novel cerebellar developmental transcriptional regulators with motif activity analysis

open access: yesBMC Genomics, 2019
Background The work of the FANTOM5 Consortium has brought forth a new level of understanding of the regulation of gene transcription and the cellular processes involved in creating diversity of cell types.
Thomas J. Ha   +17 more
doaj   +1 more source

Cyclin G and the Polycomb Repressive complexes PRC1 and PR-DUB cooperate for developmental stability. [PDF]

open access: yesPLoS Genetics, 2018
In Drosophila, ubiquitous expression of a short Cyclin G isoform generates extreme developmental noise estimated by fluctuating asymmetry (FA), providing a model to tackle developmental stability.
Delphine Dardalhon-Cuménal   +10 more
doaj   +1 more source

Developmental Regulation of dUTPase in Drosophila melanogaster [PDF]

open access: yesJournal of Biological Chemistry, 2004
dUTPase prevents uracil incorporation into DNA by strict regulation of the cellular dUTP:dTTP ratio. Lack of the enzyme initiates thymineless cell death, prompting studies on enzyme regulation. We investigated expression pattern and localization of Drosophila dUTPase.
Katalin F. Medzihradszky   +9 more
openaire   +4 more sources

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

COMPARATIVE EFFICACY OF THREE INSECT GROWTH REGULATORS ON THE DEVELOPMENTAL STAGES OF CULEX TRITAFIVIORHYNCHUS [PDF]

open access: yesJournal of Veterinary and Animal Sciences, 2010
The effect of three Insecf Growth Regulators (Diflubenzuron, Methoprene and Btf) was studied on the eggs, fourth stage larvae and pupae of Culex tritaeniorhyncus. The LCso of the insecticides was minimum when applied against 4"' stage larvae than on
Lucy Sabu, H. Subramanian
doaj  

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Negative regulation and developmental competence in Aspergillus [PDF]

open access: yesScientific Reports, 2016
AbstractAsexual development (conidiation) in the filamentous fungusAspergillus nidulansis governed by orchestrated gene expression. The three key negative regulators of conidiation SfgA, VosA, and NsdD act at different control point in the developmental genetic cascade.
Jae-Hyuk Yu   +5 more
openaire   +2 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

The Bicoid class homeodomain factors ceh-36/OTX and unc-30/PITX cooperate in C. elegans embryonic progenitor cells to regulate robust development. [PDF]

open access: yesPLoS Genetics, 2015
While many transcriptional regulators of pluripotent and terminally differentiated states have been identified, regulation of intermediate progenitor states is less well understood.
Travis Walton   +5 more
doaj   +1 more source

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