Cell-fate transition and determination analysis of mouse male germ cells throughout development
The full-term developmental profile of male germ cells remains undefined. Here, the authors use single-cell sequencing to investigate the transcriptome landscapes of mouse male germ cells throughout development and find several critical regulators for ...
Jiexiang Zhao +20 more
doaj +1 more source
Evidence linking exposure of fish primary macrophages to antibiotics activates the NF-kB pathway. [PDF]
Low doses of antibiotics are ubiquitous in the marine environment and may exert negative effects on non-target aquatic organisms. Using primary macrophages of common carp, we investigated the mechanisms of action following exposure to several common ...
Chen, Qiqing +8 more
core
Genomic Analysis of Drosophila Neuronal Remodeling: A Role for the RNA-Binding Protein Boule as a Negative Regulator of Axon Pruning [PDF]
Drosophila mushroom body (MB) {gamma} neurons undergo axon pruning during metamorphosis through a process of localized degeneration of specific axon branches.
Hoopfer, Eric D. +3 more
core +1 more source
Review and Validation of Plant Gene Function Research Methods Bypassing Tissue Culture
The genetic transformation of plants has provided fundamental insights into plant biology. However, the genetic transformation systems for most horticultural plants remain incomplete.
Huanghuang Jiang +9 more
doaj +1 more source
Development and regulation of chloride homeostasis in the central nervous system
GABA (γ-aminobutyric acid) is the main inhibitory neurotransmitter of the mature central nervous system. The developmental switch of GABAergic transmission from excitation to inhibition is induced by changes in Cl- gradients, which are generated by ...
Miho eWatanabe, Atsuo eFukuda
doaj +1 more source
Comparative Analysis of Muscle Transcriptome between Pig Genotypes Identifies Genes and Regulatory Mechanisms Associated to Growth, Fatness and Metabolism. [PDF]
Iberian ham production includes both purebred (IB) and Duroc-crossbred (IBxDU) Iberian pigs, which show important differences in meat quality and production traits, such as muscle growth and fatness.
Ayuso, Miriam +12 more
core +4 more sources
Evolution of asexual and sexual reproduction in the aspergilli [PDF]
Aspergillus nidulans has long-been used as a model organism to gain insights into the genetic basis of asexual and sexual developmental processes both in other members of the genus Aspergillus, and filamentous fungi in general.
Chen, W. +10 more
core +2 more sources
Current Advancement and Future Prospects in Simplified Transformation-Based Plant Genome Editing
Recent years have witnessed remarkable progress in plant biology, driven largely by the rapid evolution of CRISPR/Cas-based genome editing (GE) technologies.
Xueying Han +3 more
doaj +1 more source
The formation of synapses, the specialized points of chemical communication between neurons, is a highly regulated developmental process fundamental to establishing normal brain circuitry.
Thomas J F Nieland +7 more
doaj +1 more source
Background Plants respond to stress through highly tuned regulatory networks. While prior works identified master regulators of iron deficiency responses in A.
Selene R. Schmittling +4 more
doaj +1 more source

