Results 41 to 50 of about 334,033 (329)

The C. elegans tailless/Tlx homolog nhr-67 regulates a stage-specific program of linker cell migration in male gonadogenesis [PDF]

open access: yes, 2009
Cell migration is a common event during organogenesis, yet little is known about how migration is temporally coordinated with organ development. We are investigating stage-specific programs of cell migration using the linker cell (LC), a migratory cell ...
Abraham   +61 more
core   +3 more sources

Current Advancement and Future Prospects in Simplified Transformation-Based Plant Genome Editing

open access: yesPlants
Recent years have witnessed remarkable progress in plant biology, driven largely by the rapid evolution of CRISPR/Cas-based genome editing (GE) technologies.
Xueying Han   +3 more
doaj   +1 more source

Identification of novel cerebellar developmental transcriptional regulators with motif activity analysis

open access: yesBMC Genomics, 2019
Background The work of the FANTOM5 Consortium has brought forth a new level of understanding of the regulation of gene transcription and the cellular processes involved in creating diversity of cell types.
Thomas J. Ha   +17 more
doaj   +1 more source

Cellular clarity: a logistic regression approach to identify root epidermal regulators of iron deficiency response

open access: yesBMC Genomics, 2023
Background Plants respond to stress through highly tuned regulatory networks. While prior works identified master regulators of iron deficiency responses in A.
Selene R. Schmittling   +4 more
doaj   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Genome-Wide Analysis of Gene Expression during Early Arabidopsis Flower Development [PDF]

open access: yes, 2005
Detailed information about stage-specific changes in gene expression is crucial for the understanding of the gene regulatory networks underlying development.
Alves-Ferreira, Márcio   +4 more
core   +5 more sources

COMPARATIVE EFFICACY OF THREE INSECT GROWTH REGULATORS ON THE DEVELOPMENTAL STAGES OF CULEX TRITAFIVIORHYNCHUS [PDF]

open access: yesJournal of Veterinary and Animal Sciences, 2010
The effect of three Insecf Growth Regulators (Diflubenzuron, Methoprene and Btf) was studied on the eggs, fourth stage larvae and pupae of Culex tritaeniorhyncus. The LCso of the insecticides was minimum when applied against 4"' stage larvae than on
Lucy Sabu, H. Subramanian
doaj  

Cyclin G and the Polycomb Repressive complexes PRC1 and PR-DUB cooperate for developmental stability. [PDF]

open access: yesPLoS Genetics, 2018
In Drosophila, ubiquitous expression of a short Cyclin G isoform generates extreme developmental noise estimated by fluctuating asymmetry (FA), providing a model to tackle developmental stability.
Delphine Dardalhon-Cuménal   +10 more
doaj   +1 more source

A Systems Biology Approach to Identify Essential Epigenetic Regulators for Specific Biological Processes in Plants

open access: yesPlants, 2021
Upon sensing developmental or environmental cues, epigenetic regulators transform the chromatin landscape of a network of genes to modulate their expression and dictate adequate cellular and organismal responses.
Rachel M. McCoy   +5 more
doaj   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

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