Results 61 to 70 of about 357,386 (324)

A Systems Biology Approach to Identify Essential Epigenetic Regulators for Specific Biological Processes in Plants

Plants, 2021
Upon sensing developmental or environmental cues, epigenetic regulators transform the chromatin landscape of a network of genes to modulate their expression and dictate adequate cellular and organismal responses.
Rachel M. McCoy, Russell Julian, Shoban R. V. Kumar, Rajeev Ranjan, Kranthi Varala, Ying Li   +5 more
doaj   +1 more source

Ethylene-independent promotion of photomorphogenesis in the dark by cytokinin requires COP1 and the CDD complex [PDF]

, 2019
The transition of skotomorphogenesis to photomorphogenesis is induced by the perception of light, and is characterized by the inhibition of hypocotyl elongation and opening of cotyledons.
Cortleven, Anne, Ehret, Stephanie, Johansson, Henrik, Schmülling, Thomas   +3 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Cyclin G and the Polycomb Repressive complexes PRC1 and PR-DUB cooperate for developmental stability. [PDF]

PLoS Genetics, 2018
In Drosophila, ubiquitous expression of a short Cyclin G isoform generates extreme developmental noise estimated by fluctuating asymmetry (FA), providing a model to tackle developmental stability.
Delphine Dardalhon-Cuménal, Jérôme Deraze, Camille A Dupont, Valérie Ribeiro, Anne Coléno-Costes, Juliette Pouch, Stéphane Le Crom, Hélène Thomassin, Vincent Debat, Neel B Randsholt, Frédérique Peronnet   +10 more
doaj   +1 more source

Experimental Control and Characterization of Autophagy in Drosophila [PDF]

, 2008
Insects such as the fruit fly Drosophila melanogaster, which fundamentally reorganize their body plan during metamorphosis, make extensive use of autophagy for their normal development and physiology.
A.D. Velentzas, B. Ravikumar, C.Y. Lee, C.Y. Lee, D.N. Martin, F. Akdemir, G. Juhasz, J.S. Britton, K. Lindmo, K.M. Hennig, M. Sass, N.A. Theodosiou, P.H. Scott, R.C. Scott, R.C. Scott, S.E. McGuire, S.M. Gorski, T.E. Rusten, T.P. Neufeld   +18 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Multiple feedback loops through cytokinin signaling control stem cell number within the Arabidopsis shoot meristem [PDF]

, 2009
A central unanswered question in stem cell biology, both in plants and in animals, is how the spatial organization of stem cell niches are maintained as cells move through them.
Anders, Birnbaum, Brand, C. Ohno, Clark, Clark, Clark, Clark, E. M. Meyerowitz, Fletcher, Fletcher, Gallois, Gallois, Geier, Gordon, Haecker, Jasinski, Jonsson, Kayes, Kurakawa, Laux, Leibfried, Long, Mahonen, Mayer, Muller, Muller, S. P. Gordon, Sablowski, Schoof, Skoog, Tucker, V. S. Chickarmane, Yanai   +33 more
core   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Metabolic and Transcriptional Reprogramming in Developing Soybean (Glycine max) Embryos

Metabolites, 2013
Soybean (Glycine max) seeds are an important source of seed storage compounds, including protein, oil, and sugar used for food, feed, chemical, and biofuel production.
Ruth Grene, Lenwood S. Heath, Elijah Myers, Farzaneh Tabataba, Akshay Kakumanu, Curtis Klumas, Delasa Aghamirzaie, Yihui Fang, Eva Collakova   +8 more
doaj   +1 more source

The hardwiring of development: Organization and function of genomic regulatory systems [PDF]

, 1997
The gene regulatory apparatus that directs development is encoded in the DNA, in the form of organized arrays of transcription factor target sites. Genes are regulated by interactions with multiple transcription factors and the target sites for the ...
Arnone, Maria I., Davidson, Eric H.
core