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Population-based genetic effects for developmental stuttering [PDF]

open access: yesHGG Advances, 2022
Summary: Despite a lifetime prevalence of at least 5%, developmental stuttering, characterized by prolongations, blocks, and repetitions of speech sounds, remains a largely idiopathic speech disorder.
Hannah G. Polikowsky   +14 more
doaj   +5 more sources

Involvement of the Cortico-Basal Ganglia-Thalamocortical Loop in Developmental Stuttering [PDF]

open access: yesFrontiers in Psychology, 2020
Stuttering is a complex neurodevelopmental disorder that has to date eluded a clear explication of its pathophysiological bases. In this review, we utilize the Directions Into Velocities of Articulators (DIVA) neurocomputational modeling framework to ...
Soo-Eun Chang   +6 more
doaj   +6 more sources

Weak Vestibular Response in Persistent Developmental Stuttering [PDF]

open access: yesFrontiers in Integrative Neuroscience, 2021
Vibrational energy created at the larynx during speech will deflect vestibular mechanoreceptors in humans (Todd et al., 2008; Curthoys, 2017; Curthoys et al., 2019). Vestibular-evoked myogenic potential (VEMP), an indirect measure of vestibular function,
Max Gattie   +3 more
doaj   +8 more sources

Atypical gut microbiota composition in a mouse model of developmental stuttering [PDF]

open access: yesScientific Reports
Developmental stuttering is a complex neurodevelopmental disorder characterized by disfluent speech. It has been associated with mutations in genes involved in lysosomal enzyme trafficking.
Sayan Nanda   +6 more
doaj   +3 more sources

IFNAR1 gene mutation may contribute to developmental stuttering in the Chinese population [PDF]

open access: yesHereditas, 2021
Background Developmental stuttering is the most common form of stuttering without apparent neurogenic or psychogenic impairment. Recently, whole-exome sequencing (WES) has been suggested to be a promising approach to study Mendelian disorders.
Yimin Sun   +6 more
doaj   +3 more sources

A comparison of structural morphometry in children and adults with persistent developmental stuttering. [PDF]

open access: yesBrain Commun, 2023
This cross-sectional study aimed to differentiate earlier occurring neuroanatomical differences that may reflect core deficits in stuttering versus changes associated with a longer duration of stuttering by analysing structural morphometry in a large ...
Miller HE   +6 more
europepmc   +2 more sources

Effect of an Auditory Temporal Training Program on Speech Fluency of Children with Developmental Stuttering. [PDF]

open access: yesIran J Child Neurol, 2023
Objectives The present study aims to investigate the effect of a temporal processing-based auditory training program on alleviating stuttering severity in children diagnosed with auditory temporal processing disorders.
Farazi M   +4 more
europepmc   +2 more sources

The Role of Sensory Feedback in Developmental Stuttering: A Review. [PDF]

open access: yesNeurobiol Lang (Camb), 2021
Developmental stuttering is a neurodevelopmental disorder that severely affects speech fluency. Multiple lines of evidence point to a role of sensory feedback in the disorder; this has led to a number of theories proposing different disruptions to the ...
Bradshaw AR, Lametti DR, McGettigan C.
europepmc   +2 more sources

Psychedelics in developmental stuttering to modulate brain functioning: a new therapeutic perspective? [PDF]

open access: yesFront Hum Neurosci
Developmental stuttering (DS) is a neurodevelopmental speech-motor disorder characterized by symptoms such as blocks, repetitions, and prolongations. Persistent DS often has a significant negative impact on quality of life, and interventions for it have ...
Pasculli G   +9 more
europepmc   +2 more sources

White matter tract strength correlates with therapy outcome in persistent developmental stuttering. [PDF]

open access: yesHum Brain Mapp, 2022
Persistent stuttering is a prevalent neurodevelopmental speech disorder, which presents with involuntary speech blocks, sound and syllable repetitions, and sound prolongations. Affected individuals often struggle with negative feelings, elevated anxiety,
Neef NE   +7 more
europepmc   +2 more sources

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