Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Architecture and infrastructure for progress in Argentina (1960-1975): A background knowledge
The state promotion of Argentine architectural and infrastructure works in the "long 1960s" was linked to recognizable demands that emerge from territorial and economic planning.
Camila Costa
doaj
Welfare reform and future challenges in the Republic of Korea [PDF]
노트 : The author is at present Research Coordinator with the UN Research Institute for Social Development (UNRISD) while on leave from Sung Kyun Kwan University, Seoul. He has published books and articles on East Asian social policy including recent paper,
Kwon, Huck ju
core
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
A Critical Review of the End of Development, Post-Developmentalism and Development Paradigm Impasse [PDF]
Development as a specific concept for scientists, politicians, and the public has some validity, so any resistance to it needs great bravery. Despite its validity and importance‚ the development paradigm envisages with many critiques and challenges‚ so ...
Ghodrat Ahmadian
doaj
Forest frontiers out of control: The long-term effects of discourses, policies, and markets on conservation and development of the Brazilian Amazon. [PDF]
Pokorny B +3 more
europepmc +1 more source
Making the poor pay for public goods via microfinance: Economic and political pitfalls in the case of water and sanitation [PDF]
This paper critically assesses microfinance's expansion into the provision of public goods. It focuses on the problem of public goods and collective action and refers to the specific example of water and sanitation.
Mader, Philip
core
Small RNA pathways in mammalian oocytes
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
New Industries in Southeast Asia’s Late Industrialization: Evolution versus Creation - The Automation Industry in Penang (Malaysia) considered [PDF]
Discourse on industry development and policy practice in late industrialization countries in East and Southeast Asia has predominantly tended to relate the emergence of new industries to ‘creation’ by the state and thereby to the role of state ...
Leo van Grunsven
core

