Results 251 to 260 of about 16,259 (315)

NIBV Induces Incomplete Autophagy via AMPK‐TFEB, Causing Kidney Injury in Chicks

open access: yesAdvanced Science, EarlyView.
This study reveals that NIBV can inhibit the nuclear translocation of TFEB by suppressing the expression of AMPK, leading to the blockade of autophagolysosomal functions, in turn increasing NIBV replication and triggering severe kidney injury in chicks.
Cheng Huang   +10 more
wiley   +1 more source

Functional Analysis of Ligand‐Gated Chloride Channels in a Cnidarian Sheds Light on the Evolution of Inhibitory Signaling

open access: yesAdvanced Science, EarlyView.
We uncover a large variety of putative inhibitory ligand‐gated ion channels (LGICs) in the phylum Cnidaria, the sister group to all bilaterian animals. Phylogenetic analysis suggests a complex evolutionary history of inhibitory LGICs with diverse neurotransmitter ligands.
Abhilasha Ojha   +13 more
wiley   +1 more source
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From Developmental Biology to Developmental Toxicology

Annals of the New York Academy of Sciences, 2000
Abstract: Progress derived from the human genome project will have tremendous impact on toxicology. Questions concerning genetic susceptibility or resistance to toxic compound exposure and the dissection of the molecular mechanisms involved will be at the forefront of future toxicological research.
R, Balling, M, Hrabé de Angelis
openaire   +2 more sources

Developmental dyspraxia and developmental coordination disorder

Neuropsychology Review, 1995
This article discusses the role developmental dyspraxia plays in developmental coordination disorder (DCD), based upon a review of literature on apraxia, developmental dyspraxia, and DCD. Apraxia and dyspraxia have often been equated with DCD. However, it is argued that apraxia and dyspraxia primarily refer to the problems of motor sequencing and ...
M, Miyahara, I, Möbs
openaire   +2 more sources

A developmental framework for developmental dyslexia

Annals of Dyslexia, 1986
There are surprisingly few theories of the normal development of literacy that take into account the different cognitive processes underlying reading and spelling skills. The present framework suggests three phases, corresponding to the acquisition of logographic, alphabetic, and, finally, orthographic skills.
openaire   +2 more sources

Developmental Evolution*

WIREs Cognitive Science, 2016
Biologists and psychologists are re‐thinking the long‐standing premise of genes as the primary cause of development, a view widely embraced in 20th‐century biology. This shift in thinking is based in large part on: (1) the growing appreciation of the complex, distributed regulatory dynamics of gene expression; and (2) the growing appreciation of the ...
openaire   +2 more sources

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