Results 71 to 80 of about 16,040 (295)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The End of the Progressive Narrative in Latin America

open access: yesAlternautas, 2016
Are we witnessing the end of the progressive governments’ cycle in Latin America? This question seems to come up after every electoral defeat or disappear whenever there is a victory.
Salvador Schavelzon, Gerardo Muñoz
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

The social issue, development and hegemony in Argentina during the 60’s. The Onganía’s case

open access: yesUniversitas Humanística, 2010
This paper addresses the discourse conflicts concerning development and the social issue, between the government elites and the power groups during post-Peronist developmentalism era in Argentina.
Arturo Claudio Laguado Duca
doaj  

Liberal or Developmentalist? Brazil’s faces in the global financial order [PDF]

open access: yesBrazilian Journal of Political Economy
This article examines Brazil’s ambivalent stance toward the liberal global financial order. Focusing on the period from 2003 to 2022, it analyzes how successive governments alternated between liberal orthodoxy and developmentalist strategies.
LUIZ FERNANDO RODRIGUES DE PAULA   +2 more
doaj   +2 more sources

Rethinking the Emerging Post-Washington Consensus: A Critical Appraisal [PDF]

open access: yes
The objective of the paper is to provide a critical assessment of the emerging post-Washington Consensus (PWC), as a new paradigm in the development debate.
Fikret Senses, Ziya Önis
core  

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Transforming the developmental welfare states in East Asia [PDF]

open access: yes
This article attempts to explain changes and continuity in the developmental welfare states in Korea and Taiwan Province of China (hereafter Taiwan) within the East Asian context. It first elaborates two strands of welfare developmentalism (selective vs.
Huck-ju Kwon
core  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Nature Protection: the FBCN and Conservation Initiatives in Brazil, 1958-1992

open access: yesHistoria Ambiental Latinoamericana y Caribeña, 2013
The text evaluates the trajectory of the Fundação Brasileira para a Conservação da Natureza (FBCN, Brazilian Foundation for Nature Conservation).
José Luiz de Andrade Franco   +1 more
doaj  

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