Results 51 to 60 of about 12,781 (247)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

The moderating role of work skills in relationship between job stress, feeling energy and emotional exhaustion with deviant and organizational citizenship behaviors and creativity

Salāmat-i kār-i Īrān, 2013
Background and Aim : Work skills are among variables which promote the coping abilities of individuals with high job demands at workplaces. This research was administered with the aim of studying the moderating role of work skills in connection between ...
M Golparvar, Z Vaseghi, Z Javadian
doaj  

The Relationship Between Negative Leadership Behaviors and Workplace Deviant Behaviors: Moderated Mediation Examination of Loyalty to Supervisors

SAGE Open
This study explores the relationship between supervisors’ negative leadership behaviors, subordinates perceived organizational justice, and subordinates’ workplace deviant behaviors and the moderated mediation effect of subordinate loyalty to supervisors.
Tsang-Kai Hung, Shih-Liang Lee, Shu-Huei Liou, Jian-Liang Lin   +3 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Parenting Styles, Social Network and Socio-Demographic Factors on Deviant Behavior among In-School Adolescents

Psikoislamika
Deviant behaviors among in-school adolescents have been on the increased over the years. Studies that have examined different predictors of deviant behaviors have produced varied results.
Esohe Grace Ehondor, Farouk Ige Idris, Emmanuel Etim Uye   +2 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

The Impact of Ethical Social Responsibility and Spiritual Community on Occurrence of Deviant Behaviors in the Workplace: mediating role of Affective Commitment (Case of: Ferdowsi University of Mashhad)

مشاوره شغلی و سازمانی, 2019
The main purpose of this study is to investigate the impact of ethical social responsibility and spiritual Community on occurrence of deviant behaviors in the workplace considering the role of affective commitment. The sample is consisted of 600 Employee
غلامرضا ملک زاده, وسن کامل عفلوک الحسناوی, مرضیه ادیب زاده   +2 more
doaj  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

The Relationship between Toxic Leadership and Staff Nurse’s Deviant Behaviors [PDF]

Egyptian Journal of Health Care
 Background: Toxic leadership is ineffective conduct that embodies the bad or dark side of leadership and can negatively affect not only the followers but also the whole organization.
Eman Osman Elsaid Elsabagh, Reem Mabrouk Abd El Rahman, Mayada Hassan Saad Elzohairy   +2 more
doaj   +1 more source