Results 41 to 50 of about 4,750,460 (270)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Research status and prospects of solid electric heat storage technology
Zhejiang dianli, 2023 As a key component of energy storage technology， solid electric heat storage technology is adopted to convert valley electricity and various fluctuating electricity energy such as wind power and solar power into heat.
MA Meixiu +6 more
doaj +1 more source
, 1978 An electroexplosive device is presented which employs a header having contact pins hermetically sealed with glass passing through from a connector end of the header to a cavity filled with a shunt layer of a new nonlinear resistive composition and a heat-
Menichelli, V. J.
core +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
STUDYING THE POSSIBILITY OF CREATION OF TECHNICAL MEANS OF SYNCHRONIZATION OF PULSE INDICATORS [PDF]
Biomedicinskaâ Inženeriâ i Èlektronika, 2017 The scientific work is devoted to the study of the possibility of creating a technical tool for synchronization of pulse rates. The explanatory note consists of four sections. The paper describes variations of the pulse and its characteristics.
Novikova A.O. , Pankratova O.V.
doaj +1 more source
Connector locking device [PDF]
, 1970 Slidable spring-loaded locking device eliminates need for safety wiring. Locking device is placed between the connector plug and connector receptacle.
Rabb, L. W.
core +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Medicina, 2022 Background and Objectives: Shoulder disorders are associated with pain, restricted range of motion and muscular strength, moderate disability and diminished proprioception.
Alexandra Camelia Gliga +4 more
doaj +1 more source
, 1983 A clamp-mount device is disclosed for mounting equipment to an associated I-beam and the like structural member of the type having oppositely extending flanges wherein the device comprises a base and a pair of oppositely facing clamping members carried ...
Clark, K. H.
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source