Results 61 to 70 of about 4,461,023 (266)
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Barriers to medical device innovation
Medical Devices: Evidence and Research, 2014 Jacob Bergsland, Ole Jakob Elle, Erik Fosse The Intervention Centre, Oslo University Hospital, Institute of Clinical Medicine, University of Oslo, Oslo, Norway Abstract: The US Food and Drug Administration (FDA) has defined a medical device as a health ...
Bergsl, J, Elle OJ, Fosse E
doaj
Energy Efficiency and Sum Rate when Massive MIMO meets Device-to-Device Communication
, 2015 This paper considers a scenario of short-range communication, known as device-to-device (D2D) communication, where D2D users reuse the downlink resources of a cellular network to transmit directly to their corresponding receivers.
Björnson, Emil +4 more
core +3 more sources
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
IEEE Open Journal of the Communications SocietyRecent interest in Device-to-Device (D2D) communication systems, particularly by Public Safety Organizations (PSOs), arises from scenarios where no infrastructure is available.
Hussein Hammoud +5 more
doaj +1 more source
Analysis and Scheduling in a 5G Heterogeneous Content Delivery Network
IEEE Access, 2018 Caching popular multimedia content constitutes a promising solution to mitigate the congestion in the ultimate potential for 5G networks. Moreover, a three-tier heterogeneous network, where device-to-device pairs, small cells, and macro base stations ...
Mingkai Chen +6 more
doaj +1 more source
Device-to-Device Communications Enabled Energy Efficient Multicast Scheduling in mmWave Small Cells
, 2017 To keep pace with the rapid growth of mobile traffic demands, dense deployment of small cells in millimeter wave (mmWave) bands has become a promising candidate for next generation wireless communication systems.
Chen, Xinlei +5 more
core +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Universal and Versatile Magnetic Connectors for Microfluidic Devices
MicromachinesWorld-to-chip interfacing remains a critical issue for microfluidic devices. Current solutions to connect tubing to rigid microfluidic chips remain expensive, laborious, or require specialized skills and precision machining.
Maria Alvarez-Amador +2 more
doaj +1 more source
Spectrum Sharing Scheme Between Cellular Users and Ad-hoc Device-to-Device Users
, 2013 In an attempt to utilize spectrum resources more efficiently, protocols sharing licensed spectrum with unlicensed users are receiving increased attention. From the perspective of cellular networks, spectrum underutilization makes spatial reuse a feasible
Aazhang, Behnaam +2 more
core +1 more source