Results 111 to 120 of about 236,981 (311)

Peripheral plasma levels of oestradiol-17 and progesterone in the bitch during the oestrous cycle, in normal pregnancy and after dexamethasone treatment [PDF]

, 1976
R. Austad, Astrid Lunde, Ø. V. Sjaastad
openalex   +1 more source

A Compartmentalized Joint‐on‐chip (JoC) Model to Unravel the Contribution of Cartilage and Synovium to Osteoarthritis Pathogenesis

Advanced Science, EarlyView.
A compartmentalized joint‐on‐chip (JoC) platform is here developed, modelling the interactions between cartilage and synovium in osteoarthritis (OA). Using independent culture and mechanical/biochemical stimulation, the JoC revealed how inflammation and mechanical damage drive mutual tissue changes.
Cecilia Palma, Shima Salehi, Michela Anna Polidoro, Matteo Moretti, Marco Rasponi, Silvia Lopa, Paola Occhetta   +6 more
wiley   +1 more source

Establishment of a dexamethasone-induced zebrafish skeletal muscle atrophy model and exploration of its mechanisms

Experimental Gerontology
Background: Skeletal muscle atrophy is one of the main side effects of high-dose or continuous use of glucocorticoids (such as dexamethasone). However, there are limited studies on dexamethasone-induced skeletal muscle atrophy in zebrafish and even fewer
Chen-Chen Sun, Ye-Jun Li, Dan-Ting Zhu, Zhang-Lin Chen, Jiang-Ling Xiao, Xiang-Tao Chen, Lan Zheng, Xi-Yang Peng, Chang-Fa Tang   +8 more
doaj   +1 more source

Aldol Condensation of Corticoids with Formaldehyde. II. 21-Hydroxymethylation of Reichstein's Substance S, Dexamethasone and Deoxycorticosterone

, 1964
Shunsaku Noguchi, Fujiko Nakayama, Katsura Morita   +2 more
openalex   +2 more sources

The Pathogenic Roles of Local Vitamin D Metabolism Defect in Valve Inflammation and Calcification

Advanced Science, EarlyView.
This study identifies the valvular interstitial cell populations responsible for valvular calcification induced by hyperphosphatemia and likely aging, uncovers local vitamin D metabolism defect‐induced inflammation as a critical pathogenic factor of calcific aortic valve disease, and highlights active vitamin D and ERK inhibitor as potential preventive
Ruichen Yang, Chong Han, Yangli Xie, Shoutao Qiu, Shaoyang Zhang, Jingjia He, Zejian Wang, Zhenlin Zhang, Huijuan Liu, Lin Chen, Baojie Li   +10 more
wiley   +1 more source

The Effect of Dexamethasone on the Edema of Focal Cerebral Ischemia [PDF]

, 1973
ROBERT F. DONLEY, Thoralf M. Sundt
openalex   +1 more source

Life Factors and Melanoma: From the Macroscopic State to the Molecular Mechanism

Advanced Science, EarlyView.
Melanoma, an aggressive skin cancer, arises from dynamic interactions between genetic, environmental, and lifestyle factors. This review explores how age, gender, obesity, diet, exercise, smoking, alcohol, UV exposure, circadian rhythms, and medications influence melanoma risk and progression.
Hanbin Wang, Hengxiang Zhang, Yuqi Zhou, Chunying Li, Weinan Guo   +4 more
wiley   +1 more source

PVC Nanoplastics Exposure Exacerbates Asthma through R‐Loop Accumulation and Subsequent STING Activation in Macrophages

Advanced Science, EarlyView.
Polyvinyl chloride (PVC) nanoplastics (NPs) are shown to aggravate allergic airway inflammation in asthma by triggering R‐loop accumulation and activating the cGAS‐STING pathway in macrophages. This study reveals a novel immunotoxic mechanism linking environmental plastic exposure to asthma pathogenesis and highlights potential molecular targets for ...
Qimei Bao, Yixing Huang, Mingcong Deng, Chunkai Zhang, Dan Zu, Hanyi He, Yangchan Hu, Yuke Zhong, Chen Liang, Haidong Liu, Wumin Dai, Yanhua He, Yaoshu Teng, Ji Jing, Yin Shi, Xiangdong Cheng, Zu Ye   +16 more
wiley   +1 more source

Improving patient recruitment to randomised trials can be cost-effective: A case-study of dexamethasone from the RECOVERY trial.

PLoS ONE
BackgroundThe RECOVERY trial assessed the effectiveness of treatments on preventing severe outcomes from COVID-19 disease in hospitalised patients from 176 NHS hospitals. Clinical benefits of Dexamethasone were observed for hospitalised COVID-19 patients.
Athanasios Gkekas, Sarah J Ronaldson, Adwoa Parker, David J Torgerson   +3 more
doaj   +1 more source

Dexamethasone suppression of the plasma corticosterone response to stress in the rat

, 1966
R. A. DONALD
openalex   +2 more sources